Results 141 to 150 of about 66,989 (314)

Spatial and Temporal Inhomogeneity of Left Ventricular Myocardial Transmural Strains During Diastole [PDF]

Rapid early filling requires a rapid shift to a very compliant left ventricle immediately after systole, allowing filling at low driving pressures. This compliance shift is manifested as changes in transmural strains: however its mechanistic basis is ...
Ingels Jr., N. B., Langer, F., Cheng, A., Miller, D. C., Karlsson, M.,, Kindberg, Katarina,, Rodriguez, F., Daughters, G. T.   +7 more
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Evaluation of the intraventricular hemodynamics of patients with left ventricular dysfunction via vector flow mapping

Frontiers in Cardiovascular Medicine
BackgroundVorticity, measured via new vector flow mapping (VFM), a quantitative marker of vortex dynamics, can reflect hemodynamic changes more sensitively, potentially offering complementary information to conventional echocardiographic indices of ...
Qun Xu, Li Hao, Guang Yang, Mei Zhang, Mingxue Di   +4 more
doaj   +1 more source

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

Arthritis &Rheumatology, EarlyView.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu, Zhu Yan, Xueting Peng, Meixuan Li, Juan Wang, Yan Zhang, Xiaoqian Hu, Mingzhu Zhou, Kaixuan Ren, Dan Zhang, Xingyi Guo, Yumin Xia, Huanhuan Huo   +12 more
wiley   +1 more source

Finite element analysis of the human left ventricle in diastole and systole [PDF]

, 1997
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Previously, at Brunel University, two computer programs had been developed to facilitate the analysis of the diastolic material properties of the human left
Beecham, MC, Beecham, M.
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MDCT evaluation of dynamic changes in aortic root parameters during the cardiac cycle in patients with aortic regurgitation

Scientific Reports
Objectives: To investigate the dynamic changes in multiple planes and parameters of the aortic root region at different phases of the cardiac cycle in patients with aortic regurgitation (AR) using multi-detector row computed tomography (MDCT). To provide
Shuai Zhang, Ting Huang, Yun Lu, Xi Guo, Quanliang Shang   +4 more
doaj   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Calcium Homeostasis of the Myocardium at Diastole [PDF]

, 2017
Kardiyak miyositlerdeki uyarılma-kasılma ilişkisi hücre içi kalsiyum (Ca++) taşıma mekanizmaları tarafından düzenlenmektedir. Diyastol süreci, ventriküllerin kan ile yeterli dolumu için oldukça önemlidir.
Zehra Gül Koçaklı, Kübra Akıllıoğlu, Ayşe Doğan   +2 more
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