Results 231 to 240 of about 1,526,915 (347)

A first‐trimester mechanistic framework integrating three Physiopathologic biomarker domains for pre‐eclampsia classification

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To develop and internally validate a mechanistic, three‐domain framework for early classification and prediction of pre‐eclampsia (PE) using first‐trimester angiogenic, uteroplacental, and maternal vascular biomarkers. Methods In a prospective cohort of 1925 singleton pregnancies screened at 11 to 13.6 weeks, placental growth factor (
Johnatan Torres‐Torres   +8 more
wiley   +1 more source

Effects of ranolazine in a model of doxorubicin‐induced left ventricle diastolic dysfunction

open access: yesBritish Journal of Pharmacology, 2017
D. Cappetta   +13 more
semanticscholar   +1 more source

Hypertensive retinopathy in pre‐eclampsia and its association with disease severity and neonatal outcomes: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Introduction Pre‐eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes ...
Gabriele Saccone   +6 more
wiley   +1 more source

Neurokinin-1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic mice. [PDF]

open access: yesBr J Pharmacol
Widiapradja A   +11 more
europepmc   +1 more source

diastolic dysfunction

open access: yesJournal of JCS Cardiologists, 1994
openaire   +2 more sources

Second‐trimester multimetabolite panel for early preeclampsia rule‐out

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins   +7 more
wiley   +1 more source

Validation of the fullPIERS model for predicting severe maternal outcomes in preeclampsia in five Brazilian centers

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The objective of this study is to validate the fullPIERS (Pre‐eclampsia Integrated Estimate of Risk) prognostic model in a large, multicenter cohort of Brazilian women with preeclampsia and to determine the optimal cutoff for clinical application in the Brazilian context.
Pedro do Valle Teichmann   +8 more
wiley   +1 more source

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