Efficient identification of myocardial material parameters and the stress-free reference configuration for patient-specific human heart models [PDF]
Image-based computational models of the heart represent a powerful tool to shed new light on the mechanisms underlying physiological and pathological conditions in cardiac function and to improve diagnosis and therapy planning. However, in order to enable the clinical translation of such models, it is crucial to develop personalized models that are ...
arxiv
Primary diastolic failure is typically seen in patients with hypertensive or valvular heart disease as well as in hypertrophic or restrictive cardiomyopathy but can also occur in a variety of clinical disorders, especially tachycardia and ischemia ...
Eberli, Franz R.+3 more
core
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin+17 more
wiley +1 more source
A Novel Mathematical/Numerical Formula for Assessing Right Ventricular Torsion Using Echocardiographic Imaging [PDF]
Recently, the ventricular torsional parameters have received special attention because of their significant role in the ventricular systolic and diastolic function. Right ventricular (RV) rotational deformation is a sensitive index for RV performance but difficult to measure.
arxiv
Do patients with suspected heart failure and preserved left ventricular systolic function suffer from "diastolic heart failure" or from misdiagnosis? A prospective descriptive study [PDF]
OBJECTIVES: To characterise the clinical features of patients with suspected heart failure but preserved left ventricular systolic function to determine if they have other potential causes for their symptoms rather than being diagnosed with 'diastolic ...
Caruana, L.+3 more
core +2 more sources
Biomechanical‐to‐electrical energy conversion devices are uniquely suited for self‐driven physiological information monitoring and powering human–computer interaction systems. These devices based on micro‐/nanoarchitectured inorganic dielectric materials (MNIDMs) have shown ultrahigh electromechanical performance and thus great potential for practical ...
Jia‐Han Zhang+12 more
wiley +1 more source
The Effect of Metformin on Diastolic Function in Patients Presenting with ST-Elevation Myocardial Infarction. [PDF]
Diastolic dysfunction is an important predictor of poor outcome after myocardial infarction. Metformin treatment improved diastolic function in animal models and patients with diabetes. Whether metformin improves diastolic function in patients presenting
Lawien Al Ali+9 more
doaj +1 more source
A Wavelet Approach for the Estimation of Left Ventricular Early Filling Wave Propagation Velocity from Color-M-Mode Echocardiograms [PDF]
Objective: This work evaluates a new approach for calculating the left-ventricular (LV) early filling propagation velocity (VP) from color M-Mode (CMM) echocardiograms using wavelet analysis. Unlike current approaches, the method requires no assumptions, user inputs, or heuristic conventions.
arxiv
The effects of continous positive airway pressure on LV diastolic function in patients with obstructive sleep apnea [PDF]
Background and aims: One of the main problems of health is Obstructive Sleep Apnea (OSA). The aim of the present study was to determine the effects of Continous Positive Airway Pressure (CPAP) on Left Ventricular (LV) diastolic function in patients ...
Saneei, Hamid., Yosefi, Ali.
core
Materials Advances in Devices for Heart Disease Interventions
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra+11 more
wiley +1 more source