Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang +22 more
wiley +1 more source
A Hybrid Diffusion Model Enhances Multiparametric 3D Photoacoustic Computed Tomography
The hybrid diffusion PACT (HD‐PACT) system enhances dynamic multiparametric information using only 128–256 ultrasound elements. By overcoming limited‐view artifacts, HD‐PACT refines structural and functional information such as oxygen saturation observed in 3D premium PACT with > 1000 elements. Through cost‐effective and faster multiparametric imaging,
Hyunsu Jeong +5 more
wiley +1 more source
Association of Metabolic Dysfunction-Associated Fatty Liver Disease With Left Ventricular Diastolic Function and Cardiac Morphology [PDF]
Dandan Peng +12 more
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Metabolomics analyses reveal that trigonelline is markedly reduced in HFpEF hearts. Trigonelline supplementation alleviates metabolic disorders and improves cardiac function in HFpEF mice via gut microbiota‐mediated AMPK activation. Abstract Heart failure with preserved ejection fraction (HFpEF) is a prevalent end‐manifestation of cardiovascular ...
Zhe Cheng +9 more
wiley +1 more source
Family History of Hypertension Influences Left Ventricular Diastolic Function During Chronic Antihypertensive Therapy [PDF]
Andrea Grandi +8 more
openalex +1 more source
Autonomous Polymer Frameworks for Sustainable Tissue‐Interfaced Plastic Bioelectronics
This review focuses on plastic bioelectronic systems integrated with autonomous polymer frameworks (auto‐POFs) and summarizes recent progress in this field. It provides an in‐depth analysis of the design strategies and operational mechanisms of auto‐POFs, highlighting their pivotal role in enhancing the sustainability and interfacial adaptability of ...
Elvis K. Boahen +8 more
wiley +1 more source
Functional and metabolic imaging of the right ventricle: short-term caloric restriction increases myocardial triglyceride content and decreases diastolic heart function [PDF]
Sebastiaan Hammer +5 more
openalex +1 more source
12‐HETE Is an Endogenous Modulator of BLT2 Triggering Vascular Degeneration, Dissection, and Rupture
In thoracic aortic dissection (TAD), elevated levels of the arachidonic acid metabolite 12‐HETE, produced by macrophage‐specific 12/15‐lipoxygenase (12/15‐LOX), bind to the BLT2 receptor on vascular cells. This activates the NOX‐1/ROS/NF‐κB signaling pathway, leading to IL‐6 release.
Yuyu Li +13 more
wiley +1 more source
HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis
This study investigates the impact of iron homeostasis on exercise. Loss of the HECT domain‐containing ubiquitin ligase E3 (HUWE1) in skeletal muscle restrains the exercise performance in mice with downregulated ferroportin expression leading to iron overload, which is ameliorated by dietary iron restriction.
Huike Jiao +10 more
wiley +1 more source

