Results 161 to 170 of about 5,524,771 (289)

Addressing Key Limitations of Diastolic Function Assessment in Mouse Echocardiography by Enabling Robust Retrospective Analysis From a Standard Imaging View. [PDF]

open access: yesActa Physiol (Oxf)
Marterstock M   +9 more
europepmc   +1 more source

Clinical Outcomes of the Allegra Transcatheter System in Bioprosthetic Aortic Valve Failure: A Multicentre Valve‐in‐Valve Registry

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Introduction The prevalence of bioprosthetic aortic valve failure is increasing due to the broader use of bioprosthetic valves, both surgical and transcatheter, and an ageing population. Registry data indicate a higher risk of coronary obstruction and elevated gradients following valve‐in‐valve transcatheter aortic valve implantation (TAVI ...
Hilal Khan   +14 more
wiley   +1 more source

Cardiac magnetic resonance imaging diastolic function assessment in preserved ejection fraction and absence of late gadolinium enhancement. [PDF]

open access: yesJ Cardiovasc Magn Reson
Pan JA   +9 more
europepmc   +1 more source

Noise‐Blocking Interfacial Lamination of Small‐Molecule Acceptors for Enhanced Signal Clarity in Organic Photodetectors

open access: yesCarbon Energy, EarlyView.
The structural design strategy employing the Y6‐BO interfacial lamination suppresses dark current by limiting solvent‐induced interfacial damage through the formation of uniformly arranged interfaces while optimizing charge transport to achieve superior detectivity.
Jihyun Lim   +4 more
wiley   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović   +11 more
wiley   +1 more source

Characterization of the Immune Response after Oral Cholera Vaccination (OCV) and Effects of Mycophenolate Mofetil on Priming of this Immune Response—A Randomized, Placebo‐Controlled Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse   +4 more
wiley   +1 more source

Evaluating biventricular diastolic function using cardiovascular magnetic resonance 4d-flow derived E/e'. [PDF]

open access: yesEur Heart J Imaging Methods Pract
Grob L   +14 more
europepmc   +1 more source

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz   +5 more
wiley   +1 more source

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