Results 41 to 50 of about 303,255 (255)

Microvascular Damage Is Associated With Carotid Wall Structural Changes in Systemic Sclerosis: A Capillaroscopy and Ultrasound‐Based Observational Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source

Diastolic Function Gets Personal

JACC: Cardiovascular Imaging, 2019
![Figure][1] ![Figure][1] Exertional dyspnea is one of the most common symptoms in cardiology, and thus is also a major indication for cardiac imaging. Diastolic ventricular dysfunction is often a prime suspect for a cardiac etiology of exertional dyspnea.
Frank A, Flachskampf, Y, Chandrashekhar
openaire   +2 more sources

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Alterations in plasma triglycerides and ceramides: links with cardiac function in humans with type 2 diabetes

Journal of Lipid Research, 2020
Cardiac dysfunction in T2D is associated with excessive FA uptake, oxidation, and generation of toxic lipid species by the heart. It is not known whether decreasing lipid delivery to the heart can effect improvement in cardiac function in humans with T2D.
Linda R. Peterson, Xuntian Jiang, Ling Chen, Anne C. Goldberg, Marsha S. Farmer, Daniel S. Ory, Jean E. Schaffer   +6 more
doaj   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

State of Left Ventricular Systolic and Diastolic Function in Patients with Postinfarction Cardiosclerosis and Obesity

Mìžnarodnij Endokrinologìčnij Žurnal, 2014
Cardiovascular diseases are one of the major causes of mortality worldwide, the main contribution to its structure belongs to ischemic heart disease. One of the major factors for the progression of ischemic heart disease is obesity.
P.P. Kravchun
doaj   +1 more source

Lidocaine administered at a continuous rate infusion does not impair left ventricular systolic and diastolic function of healthy rabbits sedated with midazolam

Veterinary and Animal Science, 2020
Lidocaine is a versatile drug that not only provides local anesthesia, but also reduces anesthetic requirements of other agents and has antiarrhythmic, pro-kinetic, anti-inflammatory, antiendotoxemic and antioxidant effects. As it is a drug commonly used
A.E.G.W. Marques, M.G. Marques, B.C.R. Silveira, S.P. Oliveira, I.G. Ferraz, A.B.G. Ventricci, N.C. Silva, W.B. Nagata, B.P. Floriano, W.L. Ferreira, P.S P. Santos   +10 more
doaj   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Diastolic function and new-onset atrial fibrillation following cardiac surgery

Annals of Cardiac Anaesthesia, 2015
Background: Numerous studies have reported predictors of new-onset postoperative atrial fibrillation (POAF) following cardiac surgery, which is associated with increased length of stay, cost of care, morbidity, and mortality.
David W Barbara, Kent H Rehfeldt, Juan N Pulido, Zhuo Li, Roger D White, Hartzell V Schaff, William J Mauermann   +6 more
doaj   +1 more source

Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell Disease. [PDF]

PLoS ONE, 2016
Diastolic dysfunction is common in sickle cell disease (SCD), and is associated with an increased risk of mortality. However, the molecular pathogenesis underlying this development is poorly understood.
Julio D Duarte, Ankit A Desai, Justin R Sysol, Taimur Abbasi, Amit R Patel, Roberto M Lang, Akash Gupta, Joe G N Garcia, Victor R Gordeuk, Roberto F Machado   +9 more
doaj   +1 more source