Results 161 to 170 of about 43,478 (251)

Prevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5‐GABAA receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4836-4854, August 2026.
Background and Purpose Long‐lasting cognitive deficits after surgery in aged individuals, referred to as perioperative neurocognitive disorder (NCD), are a significant public health concern. Such postoperative cognitive deficits are dependent on the presence of microglia in the brain, which, when activated, trigger neuroinflammation.
Jinrui Lyu, Rajasekar Nagarajan, Dishary Sharmin, Prithu Mondal, Maltesh Kambali, Muxiao Wang, Jinyan Zhou, Makoto Inoue, James M. Cook, Uwe Rudolph   +9 more
wiley   +1 more source

Caffeic acid phenethyl ester protects mice against nicotine-induced seizures by attenuating oxidative stress and inflammation. [PDF]

Res Pharm Sci
Badiee MS, Vadizadeh A, Moosavi M, Fakhredini F, Kalantar H, Asl SR, Khodayar MJ.   +6 more
europepmc   +1 more source

Pharmacological Influences on the R2 Blink Reflex Response in Healthy Participants: A Systematic Review

European Journal of Neuroscience, Volume 64, Issue 3, August 2026.
Pharmacological modulation of the R2 blink reflex was comparable whether responses were elicited using standard patch or concentric electrodes. Across nine studies, noradrenergic and GABAergic interventions produced the most consistent effects, supporting the R2 blink reflex as a sensitive biomarker of trigeminofacial nociceptive processing.
Josh Murphy, Joy Krecke, Celia Morgan, Paul H. Strutton, Kirsty Bannister, Sam W. Hughes   +5 more
wiley   +1 more source

Unlocking the potential of bone marrow in postmortem forensic toxicology: current evidence and future perspectives. [PDF]

J Anal Toxicol
Vanerio S, Galante N, Ravelli A, Bergamaschi RF, Battistini A, Casati S.   +5 more
europepmc   +1 more source

Balancer‐assisted sling recovery of critical equine patients after general anaesthesia

Equine Veterinary Education, Volume 38, Issue 8, Page 412-421, August 2026.
Summary Background Traditional sling‐based systems to assist horses during recovery from general anaesthesia (GA) could be improved by adding a balancer to obtain a dynamic weight relief. Objectives To evaluate the applicability of a novel balancer‐assisted sling system during recovery of horses after GA and to report initial experiences with high‐risk
J. Kuhlmann, C. Spadavecchia, C. Koch
wiley   +1 more source

Visual-acoustic thigmotaxis in zebrafish larvae: a high throughput NAM for neurotoxicity assessment. [PDF]

Front Toxicol
Torres-Ruiz M, Muñoz-Palencia M, De la Vieja A, Cañas-Portilla AI.   +3 more
europepmc   +1 more source

Pellagra in Contemporary Clinical Practice (2000–2023): A Systematic Review

International Journal of Dermatology, Volume 65, Issue 8, Page 1590-1599, August 2026.
This systematic review (2000–2023) of 1212 cases highlights pellagra's evolving etiology. While primary dietary deficiency (85%) persists in humanitarian crises, secondary forms from alcohol misuse (9.6%), isoniazid (14.3% of drug‐related cases), and malabsorption are rising.
Noureddine Litaiem, Karama Sboui, Faten Zeglaoui   +2 more
wiley   +1 more source

Familial SCN1A-Related Epilepsy in Palestinian Siblings: Challenges of Genetic Testing in Resource-Limited Settings: A Case Report. [PDF]

Clin Case Rep
Abu Hetta A, Razem RS, Shahateet S, Pujee BK, Shawabka AM, AbuIrayyeh BM.   +5 more
europepmc   +1 more source

Triggers, Responses, and Outcomes for Patient Related Violence and/or Aggression Events During Acute Hospitalisation: A Documentary Analysis

Journal of Clinical Nursing, Volume 35, Issue 8, Page 3418-3430, August 2026.
ABSTRACT Aim To examine triggers, responses, and outcomes for patient‐related violence and/or aggression events during acute hospitalisation. Design This was a descriptive observational study undertaken at two healthcare organisations. Methods Pre‐existing data were extracted from organisational incident reports and individual medical records during a ...
Debra Kerr, Alison M. Hutchinson, Elisa Ilarda, Louise Alexander, Susan Perlen, Nicole Davies, Trish Mant, Angela Skazlic, Joanna Petrunic, Rachel Mrhar, Adam Searby   +10 more
wiley   +1 more source

Hochuekkito attenuates anxiety-like behavior associated with pulmonary inflammation induced by intratracheal lipopolysaccharides in mice. [PDF]

Front Pharmacol
Izushi Y, Ushio S, Ueda T, Tasaka Y, Miyazaki I, Asanuma M, Kitamura Y.   +6 more
europepmc   +1 more source