In vitro γ-aminobutyric acid A (GABA<sub>A</sub>) receptor activity and binding interactions at the α<sup>+</sup>/γ<sub>2</sub><sup>-</sup> interface of 53 prescription and designer benzodiazepines. [PDF]
Norman C +4 more
europepmc +1 more source
ABSTRACT We undertook a computational investigation and evaluation of the impact of maternal supplementation with baru almonds (Dipteryx alata Vog.) on anxiety‐like behavior and oxidative stress in the brains of adolescent and adult rat offspring. Molecular docking studies were conducted and revealed that the phenolic compounds (PCs) from the baru ...
Diego Elias Pereira +12 more
wiley +1 more source
Analysis of Illicit Street Heroin Seized in Pakistan by Gas Chromatography-Mass Spectrometry (GC-MS) for Identification of Adulterants and Impurities. [PDF]
Usman M +4 more
europepmc +1 more source
In a randomized, double‐blind study of individuals with alcohol use disorder, high‐dose baclofen (75 mg/day) compared with placebo was associated with differences in resting‐state functional connectivity, with higher connectivity in reward and stress‐related regions and lower connectivity in attentional and salience networks.
Warren B. Logge +5 more
wiley +1 more source
Rational Use of Benzodiazepines in Modern Healthcare: Evidence-Based Strategies. [PDF]
Samardžić J, Tandon N, Branković M.
europepmc +1 more source
Surgical management of carpus valgus deformity caused by persistent ulna in three large breed foals
Summary This case series describes the occurrence of persistent ulnar remnants in three large breed foals presented with bilateral carpus valgus deformity. Distal ulnar ossification was diagnosed based on lateromedial radiographic projections. Treatment included distal ulna ostectomy in conjunction with transphyseal screw placement or periosteal ...
A. C. Müller +4 more
wiley +1 more source
Green-synthesized <i>Matricaria chamomilla</i> silver nanoparticles enhance anticonvulsant and neuroprotective effects through GABAergic and antioxidant pathways in an acute seizure rat model. [PDF]
Alhamhoom Y +9 more
europepmc +1 more source
Summary A 17‐year‐old Swiss Warmblood mare presented with signs of left‐sided facial nerve paralysis and was diagnosed with left‐sided temporohyoid osteoarthropathy (THO). A partial ceratohyoidectomy was performed in the standing, sedated mare to treat this condition.
J. Kuhlmann +5 more
wiley +1 more source
Preclinical signal for a disease-modifying effect on seizure cluster severity with intermittent diazepam treatment. [PDF]
Wu Q +8 more
europepmc +1 more source

