Results 241 to 250 of about 109,445 (330)

The rise and fall of “Nippon no utsu‐byo ニッポンのうつ病” (the concept of Nippon depressive disease) in Japan

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 3, September 2025.
Abstract From around 1960 to 2000, Japanese psychiatrists used their own concept of depression (Utsu‐byo うつ病). To distinguish this from major depressive disorder (MDD), the present concept of depression according to the revised version of the Diagnostic and Statistical Manual of Mental Disorders, 5th edition, the present author refers to this concept ...
Susumu Ohmae
wiley   +1 more source

Sudden Sensorineural Hearing Loss in an Immunocompetent Patient With West Nile Encephalitis

open access: yesLaryngoscope Investigative Otolaryngology, Volume 10, Issue 4, August 2025.
ABSTRACT Objective Sudden sensorineural hearing loss (SSNHL) is a frequently encountered condition that is often idiopathic but may be precipitated by infection. Neuroinvasive disease resulting from West Nile virus (WNV) is a rare cause of SSNHL, typically affecting immunocompromised patients and generally associated with minimal hearing recovery.
Raj Malhotra   +3 more
wiley   +1 more source

Anticonvulsant Potential and Toxicological Profile of <i>Verbesina persicifolia</i> Leaf Extracts: Evaluation in Zebrafish Seizure and <i>Artemia salina</i> Toxicity Models. [PDF]

open access: yesPlants (Basel)
López-Rosas CA   +7 more
europepmc   +1 more source

Microglial Transient Receptor Potential Melastatin 2 Deficiency Accelerates Seizure Development via Increasing AMPAR‐Mediated Neuronal Excitability

open access: yesMedComm, Volume 6, Issue 8, August 2025.
The deficiency of transient receptor potential melastatin type 2 (TRPM2) channel as a calcium permeable nonselective cation channel, accelerates seizure development in various mouse seizure models including PTZ‐, KA‐, and kindling‐induced models, but does not affect seizure susceptibility in initial acute seizure. Interestingly, the deficiency of TRPM2
Yingwei Xu   +16 more
wiley   +1 more source

Pleiotropic Effects of the NSAID Fenamates on Chloride Channels: Opportunity for Ion Channelopathies?

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Chloride channels are involved in many cellular processes, including cell volume regulation, modulation of cell excitability, and electrolyte and water secretion. Mutations of these proteins are associated with heterogeneous diseases such as myotonia, cystic fibrosis, epilepsy, deafness, lysosomal storage disease, and various kinds of renal ...
Paola Laghetti   +4 more
wiley   +1 more source

Toxicological analyses of the bone matrix: Successes and challenges

open access: yesArchaeometry, Volume 67, Issue 4, Page 1001-1021, August 2025.
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano   +3 more
wiley   +1 more source

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