Results 21 to 30 of about 529 (153)

Regioirregular and catalytic Mizoroki-Heck reactions [PDF]

, 2021
[EN] The palladium-catalysed cross-coupling reaction between alkenes and aryl halides (the Mizoroki-Heck reaction) is a powerful methodology to construct new carbon-carbon bonds.
Boronat Zaragoza, Mercedes, Castellanos-Soriano, Jorge, Garnes-Portoles, Francisco, Greco, Rossella, Hernández-Garrido, Juan Carlos, Jiménez Molero, María Consuelo, Leyva Perez, Antonio, Lopez-Haro, Miguel, Oliver-Meseguer, Judit, Pérez-Ruiz, Raúl   +9 more
core   +1 more source

Spectrofluorimetric determination of some dibenzazepine drugs

Bulletin of Pharmaceutical Sciences. Assiut, 1999
A convenient and sensitive spectrofluorimetric method for the detn. of 6 dibenzazepine drugs: imipramine-​HCl, desipramine-​HCl, clomipramine-​HCl, trimipramine maleate, opipramol-​2HCl and carbamazepine was developed.  The method depends on the oxidn. of the compds. with potassium dichromate in acid medium.
Horria Mohamed, Ibrahim Refaat
openaire   +1 more source

A stability indicating liquid chromatography method for the assay of rufinamide bulk material and tablets [PDF]

, 2019
A simple, rapid, isocratic stability indicating reverse phase liquid chromatography method was developed for the assay of rufinamide bulk drug and tablets.
Abuga, K.O., Ngumo, P.M., Njogu, P.M., Ongarora, D.S.B.   +3 more
core   +2 more sources

Electrochemical installation of CFH2−, CF2H−, CF3−, and perfluoroalkyl groups into small organic molecules [PDF]

, 2021
Electrosynthesis can be considered a powerful and sustainable methodology for the synthesis of small organic molecules. Due to its intrinsic ability to generate highly reactive species under mild conditions by anodic oxidation or cathodic reduction ...
Delgado, José A. C., Fernandes, Vitor A., Häring, Andreas P., Kisukuri, Camila M., Paixão, Márcio W., Waldvogel, Siegfried R.   +5 more
core   +1 more source

Modern Synthetic Procedures for the Fluorination of Organic Molecules [PDF]

, 1985
In view of the number and diversity of publications on organofluorine chemistry in the recent years, it is evident that, since presenting the first series «Fluorierungsmethoden in der Organischen Chemie», fluorination reactions remain of general interest.
Haas, Alois, Lieb, Max
core   +2 more sources

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease

Angewandte Chemie, Volume 137, Issue 6, February 3, 2025.
Patients with Alzheimer's disease need immediate help. In this work, we present a new approach to treating cognitive deficits alongside the psychological symptoms of dementia. Through a combination of biological screening, crystallography, and computational methods, we have developed an innovative drug candidate – a dual modulator of cholinergic and ...
Dawid Panek, Anna Pasieka, Jakub Jończyk, Milena Gawlińska, Paula Zaręba, Agata Siwek, Małgorzata Wolak, Barbara Mordyl, Monika Głuch‐Lutwin, Gniewomir Latacz, Xavier Brazzolotto, Fabien Chantegreil, Florian Nachon, Jana Zdarova Karasova, Jaroslav Pejchal, Martin Mzik, Vit Sestak, Lukas Prchal, Jitka Odvarkova, Ondrej Soukup, Jan Korabecny, Ales Sorf, Marie Hamsikova, Lucie Zemanova, Lubica Muckova, Nela Vánova, Pola Dryja, Kinga Sałat, Georg Höfner, Klaus Wanner, Anna Więckowska, Barbara Malawska   +31 more
wiley   +2 more sources

Fluorescent Behavior of Dibenzazepine-containing Polymers in Epoxy Resin

Analytical Sciences, 2020
Dibenzazepine derivatives were added to epoxy resin (bisphenol A diglycidyl ether, DGEBA). DSC analyses showed that DGEBA could be cured by the addition of secondary and tertiary alkylamine-type compounds, but not by the addition of an N-butoxycarbonyl substituted compound. Curing of the cast film and the adhesion of glass substrates by a dibenzazepine-
Hideki, Hayashi, Yuzo, Ishigaki, Mistuo, Oda   +2 more
openaire   +3 more sources

Recommendations for treatment strategies in people with epilepsy during times of shortage of antiseizure medications [PDF]

, 2022
In times of severe antiseizure medication (ASM) shortage due to emergency situations (e.g., disasters, conflicts, sudden disruption to international supply chains), management of people with epilepsy with available ASMs can be difficult.
Asadi-Pooya, Ali A, Cross, J Helen, Mazurkiewicz-Beldzinska, Maria, Patel, Archana A, Trinka, Eugen, Welty, Timothy E   +5 more
core  

Heterocyclic Electrochemistry: Renewable Electricity in the Construction of Heterocycles [PDF]

, 2023
Numerous applications in the realm of biological exploration and drug synthesis can be found in heterocyclic chemistry, which is a vast subject. Many efforts have been developed to further improve the reaction conditions to access this interesting family
Ahmed, Nisar, Aslam, Samina, Fatima, Aroog, Rani, Sadia, Saad, Manal, Sbei, Najoua   +5 more
core   +2 more sources

Radioimmunoassay of Dibenzazepines and Dibenzcycloheptanodienes in Body Fluids and Tissues [PDF]

Clinical Chemistry and Laboratory Medicine, 1991
In an attempt to establish a radioimmunoassay (RIA), imipramine and amitriptyline immunogens were prepared; desmethyl derivatives were converted into hemisuccinates, conjugated with bovine serum albumin and used for rabbit immunization. [3H]Amitriptyline (4.3 TBq/mmol) and [3H]imipramine (2.9 TBq/mmol) were prepared by catalytic dehalogenation or ...
Krulik, R., Exner, J., Fuksová, Květa, Píchová, Dana, Beitlová, Dana, Sikora, J.   +5 more
openaire   +3 more sources