Results 61 to 70 of about 211 (73)

An encouraging progress report on the treatment of progeria and its implications for atherogenesis. [PDF]

Circulation, 2014
Oshima J, Hisama FM, Martin GM.
europepmc   +1 more source

Asenapine in the management of impulsivity and aggressiveness in bipolar disorder and comorbid borderline personality disorder: an open-label uncontrolled study. [PDF]

Int Clin Psychopharmacol, 2018
Aguglia A, Mineo L, Rodolico A, Signorelli MS, Aguglia E.   +4 more
europepmc   +1 more source

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Acid‐dependent Divergent Conversion of ortho‐Arylcyclopropanecarbonyl Carboxaldehydes for the Synthesis of Furanodibenzocycloheptenes and Dibenzocycloheptenes

Asian Journal of Organic Chemistry, 2022
Abstractortho‐Arylcyclopropanecarbonyl carboxaldehydes were utilized common substrates for the synthesis of furanodibenzocycloheptenes and dibenzocycloheptenes. Excess amount of (+)‐camphorsulfonic acid ((+)‐CSA) could lead to acid‐promoted cyclopropane ring opening/cyclization reaction of the common substrates to give dibenzocycloheptene products in ...
Nitwaree Palavong, Jantra Jantrapirom, Jumreang Tummatorn, Charnsak Thongsornkleeb, Somsak Ruchirawat   +4 more
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Labilization of C—N Linkages by Dibenzocyclohepten-5-yl Ring System

Journal of Pharmaceutical Sciences, 1974
The hydrolysis of several 5-aminodibenzo[a,d]cycloheptenes is discussed. The relative reactivity of the various compounds was closely related to the amino substituents at position 5 of the tricyclic nucleus. Both secondary and tertiary amines were prepared.
H V, Maulding, A F, Michaelis, J P, Nazareno   +2 more
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New Bioactive Prenylflavonoids and Dibenzocycloheptene Derivative from Roots of Dendrolobium lanceolatum

Journal of Natural Products, 2004
Two new flavanones (1 and 2), a new flavan (3), and a new rare dibenzocycloheptene derivative (4) together with a known flavan, 4'-hydroxy-2' ',2' 'dimethyl-pyranoflavan (5), were isolated from the roots of Dendrolobium lanceolatum. Their structures were established on the basis of spectral evidence, and an X-ray analysis was performed to confirm the ...
Somdej, Kanokmedhakul, Kwanjai, Kanokmedhakul, Komkrich, Nambuddee, Palangpon, Kongsaeree   +3 more
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Synthesis of Dibenzocyclohepten-5-ones by Electrophilic Iodocyclization of 1-([1,1′-Biphenyl]-2-yl)alkynones

The Journal of Organic Chemistry, 2014
A synthesis of iodo-substituted dibenzocyclohepten-5-ones by the iodine monochloride (or iodine)-induced intramolecular 7-endo-dig cyclization of 1-([1,1'-biphenyl]-2-yl)alkynones is reported. Detailed investigations on the substituent effects during the electrophilic iodocyclization of the alkynones show that they play a crucial role in determining ...
Yu, Chen, Chenlong, Huang, Xiaochen, Liu, Eliyahu, Perl, Zhiwei, Chen, Jieun, Namgung, Gopal, Subramaniam, Gan, Zhang, William H, Hersh   +8 more
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ChemInform Abstract: VERBINDUNGEN MIT ANTIDEPRESSIVER WIRKUNG 2. MITT. DIBENZOCYCLOHEPTENE MIT EINER BRUECKEN‐AETHER‐STRUKTUR

Chemischer Informationsdienst. Organische Chemie, 1970
Abstractcis‐ und trans‐l0,l 1‐Dihydro‐10,1 1‐dihydroxy‐5 H‐dibenzo (a,d)cyclohepten‐ 5‐on‐acetonid (Ia)‐(Ib) reagieren mit der Grignardverbindung (II) zu den Carbinolen (IIIa)‐(IIIb), die mit p‐Toluolsulfonsäure in die cyclischen Äther (IVa)‐(IVb) übergehen, die zu (Va)‐(Vb) acetyliert werden.
M. E. CHRISTY, C. C. BOLAND, J. G. WILLIAMS, E. I. ENGELHARDT   +3 more
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Conformational Specificity in Photoinduced Intramolecular 1,7-Hydrogen Abstraction of Homonaphthoquinones with a Spiro-Linked Dibenzocycloheptene Ring

Organic Letters, 2000
[reaction: see text] Irradiation of homonaphthoquinones with spiro-linked dibenzocycloheptene rings brings about the Norrish type II reaction to give polycyclic alcohols via a stereospecific 1,7-hydrogen abstraction of the less stable twist-boat conformer.
, Kokubo, , Kawahara, , Takatani, , Moriwaki, , Kawamoto, , Oshima   +5 more
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ChemInform Abstract: Synthesis of Dibenzocyclohepten‐5‐ones by Electrophilic Iodocyclization of 1‐([1,1′‐Biphenyl]‐2‐yl)alkynones.

ChemInform, 2014
AbstractA facile method to prepare dibenzocyclohepten‐5‐ones, the core structure of allocolchicine, is reported.
Yu Chen, Chenlong Huang, Xiaochen Liu, Eliyahu Perl, Zhiwei Chen, Jieun Namgung, Gopal Subramaniam, Gan Zhang, William H. Hersh   +8 more
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Synthesis and orexigenic activity of some 1-methyl-4-piperidylidene-substituted pyrrolo[2,1-b][3]benzazepine and dibenzocycloheptene derivatives

Journal of Medicinal Chemistry, 1982
The synthesis and orexigenic activity of some unsubstituted and Bz-carboxylic acid substituted 1-methyl-4-piperidylidenepyrrolo[2,1-b][3]benzazepine and dibenzocycloheptene derivatives are described. 10,11-Dihydro-3-carboxycyproheptadine (7c) has been selected for clinical evaluation as a orexigenic agent based on its low threshold dose for increasing ...
D C, Remy, S F, Britcher, P S, Anderson, P C, Bélanger, Y, Girard, B V, Clineschmidt   +5 more
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