The role of the environment in transmission of Dichelobacter nodosus between ewes and their lambs. [PDF]
Vet Microbiol, 2015 Dichelobacter nodosus (D. nodosus) is the essential causative agent of footrot in sheep. The current study investigated when D. nodosus was detectable on newborn lambs and possible routes of transmission. Specific qPCR was used to detect and quantify the load of D. nodosus in foot swabs of lambs at birth and 5-13 h post-partum, and their mothers 5-13 h
Muzafar M +6 more
europepmc +5 more sources
Genomic heterogeneity of Dichelobacter nodosus within and between UK sheep flocks and between age groups within a flock [PDF]
BMC Microbiology, 2020 Background Footrot and interdigital dermatitis are endemic infectious diseases in all sheep farming regions, impairing welfare and production. The development of efficacious vaccines against the primary causative pathogen has been hampered by the ...
P. L. Davies +5 more
doaj +2 more sources
Genomic Evidence for a Globally Distributed, Bimodal Population in the Ovine Footrot Pathogen
mBio, 2014 Footrot is a contagious, debilitating disease of sheep, causing major economic losses in most sheep-producing countries. The causative agent is the Gram-negative anaerobe Dichelobacter nodosus. Depending on the virulence of the infective bacterial strain,
Ruth M. Kennan +11 more
doaj +2 more sources
Assessment of a rtPCR for the detection of virulent and benign Dichelobacter nodosus, the causative agent of ovine footrot, in Australia [PDF]
BMC Veterinary Research, 2018 Background Ovine footrot is a highly contagious bacterial disease of sheep, costing the Australian sheep industry millions of dollars annually. Dichelobacter nodosus, the causative agent of footrot, is a gram-negative anaerobe classed into virulent and ...
Nickala Best +7 more
doaj +2 more sources
Field Validation of a Non-carcinogenic and Eco-Friendly Disinfectant in a Stand-In Footbath for Treatment of Footrot Associated With aprV2-Positive Strains of Dichelobacter nodosus in Swiss Sheep Flocks [PDF]
Frontiers in Veterinary Science, 2022 A national control program for virulent footrot is currently planned in Switzerland. Since commonly used disinfectants either contain heavy metals or are carcinogenic, the aim of this study was to verify the effectiveness of an eco-friendly and non ...
Robin Michael Schmid +5 more
doaj +2 more sources
Characterization of two putative Dichelobacter nodosus footrot vaccine antigens identifies the first lysozyme inhibitor in the genus [PDF]
Scientific Reports, 2019 The Gram-negative anaerobic bacterium Dichelobacter nodosus (Dn) causes footrot in ruminants, a debilitating and highly contagious disease that results in necrotic hooves and significant economic losses in agriculture.
Maria Victoria Humbert +4 more
doaj +2 more sources
Evaluation of loop-mediated isothermal amplification (LAMP) assay for detection of aprV2 positive Dichelobacter nodosus in-field by secondary users [PDF]
BMC Research Notes, 2019 Objective Dichelobacter nodosus is the primary aetiological agent of footrot in sheep. Ovine footrot causes considerable economic losses and substantial animal welfare issues in the Australian sheep industry. Current methods for detecting D.
Nickala Best +3 more
doaj +2 more sources
Molecular analysis of Dichelobacter nodosus isolated from footrot in sheep in Malaysia [PDF]
Veterinary Microbiology, 1998 Pulsed field gel electrophoresis analysis of genomic DNA was used to investigate genetic diversity among Dichelobacter nodosus from footrot in sheep in Malaysia. Twelve Dichelobacter nodosus strains isolated from lesion materials from infected sheep were confirmed as Dichelobacter nodosus by polymerase chain reaction technique using the species ...
Zakaria, Zunita +5 more
openaire +4 more sources
Journal of Applied Animal Research, 2018 The aim of our study was to find the most appropriate way of sample collection from cattle feet as well as to assess simple and effective sample processing, including DNA extraction for reliable diagnosis of bacteria Dichelobacter nodosus and ...
Adriana Osová +4 more
doaj +2 more sources
Twitching motility is essential for virulence in Dichelobacter nodosus. [PDF]
J Bacteriol, 2008 ABSTRACT Type IV fimbriae are essential virulence factors of Dichelobacter nodosus , the principal causative agent of ovine foot rot. The fimA fimbrial subunit gene is required for virulence, but fimA mutants exhibit several phenotypic changes and it is not ...
Han X +8 more
europepmc +5 more sources