Detection and diversity of a putative novel heterogeneous polymorphic proline-glycine repeat (Pgr) protein in the footrot pathogen Dichelobacter nodosus [PDF]
Dichelobacter nodosus, a Gram-negative anaerobic bacterium, is the essential causative agent of footrot in sheep. Currently, depending on the clinical presentation in the field, footrot is described as benign or virulent; D.
Atiya Ul-Hassan +47 more
core +4 more sources
Understanding the molecular epidemiology of the footrot pathogen Dichelobacter nodosus to support control and eradication programs [PDF]
The Gram-negative anaerobe Dichelobacter nodosus is the primary etiologic agent of ovine footrot. Few studies of the genetic diversity and epidemiology of D. nodosus have been done, despite the economic cost and welfare implications of the disease.
Buller, N. B. +5 more
core +2 more sources
Ovine pedomics : the first study of the ovine foot 16S rRNA-based microbiome [PDF]
We report the first study of the bacterial microbiome of ovine interdigital skin based on 16S rRNA by pyrosequencing and conventional cloning with Sanger-sequencing.
A Dhawi +75 more
core +2 more sources
Delineation of the virulence-related locus (vrl) of Dichelobacter nodosus [PDF]
Dichelobacter nodosus is the primary pathogen implicated in ovine footrot. In this paper we have delineated a 27 kb locus, termed the virulence-related locus (vrl), that was essentially specific for virulent D. nodosus isolates. The precise ends of this locus were mapped and the sequences of the junction regions from the virulent strain A198 were ...
V, Haring +5 more
openaire +2 more sources
Electroporation-mediated transformation of the ovine footrot pathogenDichelobacter nodosus [PDF]
Studies on the potential virulence genes of the ovine footrot pathogen Dichelobacter nodosus have been hindered by the lack of a genetic system for this organism. In an attempt to accomplish the transformation of D. nodosus cells, we constructed a plasmid that contained part of a native D. nodosus plasmid and carried a tetracycline resistance gene that
R M, Kennan, S J, Billington, J I, Rood
openaire +3 more sources
Twitching motility is essential for virulence in Dichelobacter nodosus. [PDF]
ABSTRACT Type IV fimbriae are essential virulence factors of Dichelobacter nodosus , the principal causative agent of ovine foot rot. The fimA fimbrial subunit gene is required for virulence, but fimA mutants exhibit several phenotypic changes and it is not ...
Han X +8 more
europepmc +4 more sources
Farmers' practices and factors associated with the prevalence of all lameness and lameness attributed to interdigital dermatitis and footrot in sheep flocks in England in 2004 [PDF]
The aim of this study was to investigate whether the risk factors associated with all causes of lameness in sheep differed from those associated with the lesion specific causes of lameness, interdigital dermatitis (ID) and footrot (FR).
Green, Laura E., Kaler, Jasmeet
core +1 more source
A within farm clinical trial to compare two treatments (parenteral antibacterials and hoof trimming) for sheep lame with footrot [PDF]
From observational studies, farmers who use parenteral antibacterials to promptly treat all sheep with footrot (FR) or interdigital dermatitis (ID) have a prevalence of lameness of
Abecia +38 more
core +2 more sources
A structural alignment procedure developed here enables finding and typing plasmid‐borne origin‐of‐transfer substrates in large plasmid datasets. Thousands of putative DNA transfer substrates are identified, showing that plasmid mobility can be twofold higher and span almost twofold more host species than is currently known.
Jan Zrimec
wiley +1 more source
Background Non‐healing bovine foot lesions, including non‐healing white line disease, non‐healing sole ulcer and toe necrosis, are an increasingly important cause of chronic lameness that are poorly responsive to treatment. Recent studies have demonstrated a high‐level association between these non‐healing lesions and the Treponema phylogroups ...
Gareth James Staton +4 more
wiley +1 more source

