Results 71 to 80 of about 482,321 (300)

Ordinal dose-response modeling approach for the phthalate syndrome

open access: yesEnvironment International, 2020
Background: The phthalate syndrome (PS) is a collection of related male reproductive developmental effects, ranging in severity, that have been observed in rats after gestational exposure to developmentally-toxic phthalates. For statistical purposes, the
Todd D. Blessinger   +6 more
doaj   +1 more source

Modelling of repeated ordered measurements by isotonic sequential regression [PDF]

open access: yes, 2002
The paper introduces a simple model for repeated observations of an ordered categorical response variable which is isotonic over time. It is assumed that the measurements represent an irreversible process such that the response at time t is never lower ...
Tutz, Gerhard
core   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

The Impact of Ignoring Multilevel Data Structure on the Estimation of Dichotomous Item Response Theory Models

open access: yesInternational Journal of Assessment Tools in Education, 2019
Applyingsingle-level statistical models to multilevel data typically producesunderestimated standard errors, which may result in misleading conclusions.This study examined the impact of ignoring multilevel data structure on theestimation of item ...
Hyung Rock Lee, Sunbok Lee, Jaeyun Sung
doaj   +1 more source

PANEL ESTIMATORS TO COMBINE REVEALED AND STATED PREFERENCE DICHOTOMOUS CHOICE DATA [PDF]

open access: yes
Combining stated and revealed preference data often involved multiple responses from the same individual. Panel estimators are appropriate to jointly model the decision to actually visit at current trip costs, the intention to visit at hypothetically ...
Loomis, John B.
core   +1 more source

Discovering cultural differences (and similarities) in facial expressions of emotion [PDF]

open access: yes, 2017
Understanding the cultural commonalities and specificities of facial expressions of emotion remains a central goal of Psychology. However, recent progress has been stayed by dichotomous debates (e.g., nature versus nurture) that have created silos of ...
Chen, Chaona, Jack, Rachael E.
core   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +15 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

testCompareR: an R package to compare two binary diagnostic tests using paired data [version 4; peer review: 1 approved, 2 approved with reservations]

open access: yesWellcome Open Research
Background Binary diagnostic tests are commonly used in medicine to answer a question about a patient’s clinical status, most commonly, do they or do they not have some disease.
Marc Y.R. Henrion   +2 more
doaj   +1 more source

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper   +25 more
wiley   +1 more source

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