Results 201 to 210 of about 5,599 (290)

Patient‐derived organoid‐immune co‐cultures integrated with multi‐omics reveal immunotherapy resistance mechanisms in urothelial carcinoma

open access: yesiMeta, EarlyView.
Immunotherapy resistance presents a formidable challenge in tumor biology. While fibroblast growth factor receptor 3 (FGFR3) serves as a pivotal oncogenic driver in a multitude of cancers, the exploration of its role in immune checkpoint inhibitor (ICI) resistance remains scarce, thus impeding a deeper understanding of the tumor immune microenvironment
Shan Jiang   +12 more
wiley   +1 more source

Semantic Agency Patterns Signal Depressive Experiences: Evidence From Postpartum Communication on Social Media. [PDF]

open access: yesDepress Anxiety
Witkowska M   +8 more
europepmc   +1 more source

Academic Resilience in Contexts of Inequality: Motivational and Self‐Efficacy Profiles of Disadvantaged High Achievers

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Socioeconomic disparities in academic achievement are well‐documented in France and emerge early in schooling. Yet, a subset of students from socioeconomically disadvantaged backgrounds attains high academic performance, challenging deterministic accounts of educational inequality.
Margot Rémeau   +2 more
wiley   +1 more source

Adolescents' Long‐Term Identity Tension After Politicized Cyber Shaming: Peer Support and Behavioural Visibility Management As Joint Conditions

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Politicized cyber shaming recodes adolescents' cultural interests as evidence of political loyalty or moral belonging. This study examines how such shaming is associated with longer‐term identity tension in adolescence, focusing on public expression, peer belonging, and self‐evaluation after politicized online controversy ...
Linsen Yang
wiley   +1 more source

Do Linking‐Expression Substitutions Mitigate Deterministic Interpretations of Genetic Information?

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT It is a common concern that broader audiences interpret scientific information about the genetic correlates and causes of complex human traits in an overly deterministic manner. A frequently proposed way to address this issue is to carefully select the linking expressions used to describe gene–trait relationships when communicating genetic ...
Riin Kõiv
wiley   +1 more source

Ameliorating Linguistic Anchors of Oppression

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT The words we use to represent the world shape how we interpret and respond to it; language frames what it represents. In some cases, these frames can have prejudicial effects; for example, ‘workplace flirting’ versus ‘sexual harassment’. This article examines how specific words and phrases (i.e.
Emilia L. Wilson
wiley   +1 more source

An international consensus on core reproducibility items in research. [PDF]

open access: yesPLoS Biol
Banzi R   +6 more
europepmc   +1 more source

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