Results 101 to 110 of about 178,961,087 (289)

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

The facts to the etymology of some Czech and Slovac words

Opera slavica, 2013
Etymological research is the important task of linguistics, which prove many new works published in this subject. Our study makes the etymological examination of the words common of Czech and Slovak languages cepel, cepel, which haven't clear etymology ...
Imre Pacsai
doaj  

Review of "The universal Burmese-English-Pali dictionary"

, 1982
Students of Burmese in the English speaking world have been blessed with a new Burmese-English dictionary: The Universal Burmese-English-Pali Dictionary by U Hoke Sein (for details see References below). The preface reveals that we nearly missed it.
Okell, John
core   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Peculiarities of the Use of Professionally Oriented Vocabulary by Future Agrarians while Learning English

Educational Challenges
The article is devoted to the study of the peculiarities of bilingualism of students of non-linguistic specialties when learning English. The terminological vocabulary allows accurate and accessible presentation of a content of this subject area and ...
Valentyna Malyk
doaj   +1 more source

Journeys – an introduction

Akademisk Kvarter, 2012
According to Giambattista Vico, inventive and creative thinking involves the ability to actively combine conditions in new ways and the ability to constantly observe the diverse circumstances through new perspectives.
Rune Andersen, Knud Knudsen
doaj   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

GAN-technologies in intelligent environments of the subject area

Міжнародний науково-технічний журнал "Проблеми керування та інформатики"
The paper considers the problem of applying GAN-technology in intelligent domain environments (IDEs) for the need to structure large amounts of data and generate initial knowledge.
Олена Володимирівна Горда , Юлія Володимирівна Рябчун   +1 more
doaj   +1 more source

Paediatric clonidine medication errors: Findings from a multicentre French study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to describe the characteristics of medication errors involving clonidine in paediatric patients and reported to French Network of Pharmacovigilance and Poison Control Centres. Methods This retrospective observational study analysed clonidine‐related medication errors reported between 1985 and June 2024 in patients under 12 years ...
Eve‐Marie Thillard, Anthony Facile, Marion Lepelley, Morgane Cellier, Laurent Chouchana, Sophie Gautier, Ramy Azzouz, Thierry Vial, Annie‐Pierre Jonville‐Bera   +8 more
wiley   +1 more source