Results 211 to 220 of about 667,864 (326)

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

open access: yesiMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji   +18 more
wiley   +1 more source

Evaluating Youth Participatory Action Research in the Americas: Comparative Insights on Empowerment, Methodologies, and Social Change

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Youth Participatory Action Research (YPAR) positions adolescents as co‐researchers to investigate and address social issues affecting their lives. While YPAR has gained global prominence, comparative research examining how it is conceptualized and practiced across regional contexts remains limited.
John Diaz   +5 more
wiley   +1 more source

Unveiling patterns: an exploration of machine learning techniques for unsupervised feature selection in single-cell data. [PDF]

open access: yesBrief Bioinform
Chatterjee N   +6 more
europepmc   +1 more source

Jointly Learning Structured Analysis Discriminative Dictionary and Analysis Multiclass Classifier [PDF]

open access: green, 2019
Zhao Zhang   +6 more
openalex   +1 more source

When Technology Meets Turbulence: The Impact of Digital Transformation and Policy Uncertainty on Audit Opinions

open access: yesJournal of Corporate Accounting &Finance, EarlyView.
ABSTRACT This study investigates how Corporate Digital Transformation (CDT) influences audit opinions in Chinese A‐share‐listed non‐financial firms from 2011 to 2022, with a focus on the moderating role of Economic Policy Uncertainty (EPU). Results reveal an inverted U‐shaped relationship: moderate levels of CDT enhance audit outcomes through improved ...
He Min   +2 more
wiley   +1 more source

Standardized data definitions for adult trauma video review: an expert consensus report. [PDF]

open access: yesTrauma Surg Acute Care Open
Jafari D   +9 more
europepmc   +1 more source

Trajectories of child emotional and behavioural difficulties before and during the COVID‐19 pandemic in a longitudinal UK cohort

open access: yesJCPP Advances, EarlyView.
Abstract Background There are substantial age‐related changes in emotional and behavioural problems over childhood. In order to establish the impact of the Covid‐19 pandemic on child emotional and behavioural problems, longitudinal designs which take into account age‐related trends are needed.
Nicky Wright   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy