Results 11 to 20 of about 12,893 (251)

Pesticides and breast cancer risk: a review of DDT, DDE, and dieldrin. [PDF]

open access: diamondEnvironmental Health Perspectives, 2001
Established risk factors for breast cancer explain breast cancer risk only partially. Hence, there has been interest in evaluating what role environmental chemicals, especially those with evidence of being hormonally active agents, play in breast cancer ...
Suzanne M. Snedeker
semanticscholar   +3 more sources

Reducing uncertainty in dose-response assessments by incorporating Bayesian benchmark dose modeling and in vitro data on population variability. [PDF]

open access: yesRisk Anal
Abstract There are two primary sources of uncertainty in the interpretability of toxicity values, like the reference dose (RfD): estimates of the point of departure (POD) and the absence of chemical‐specific human variability data. We hypothesize two solutions—employing Bayesian benchmark dose (BBMD) modeling to refine POD determination and combining ...
Lu EH, Ford LC, Rusyn I, Chiu WA.
europepmc   +2 more sources

A Dieldrin Case Study: Another Evidence of an Obsolete Substance in the European Soil Environment

open access: yesAgriculture, 2021
Soil constitutes a central environmental compartment that, due to natural and anthropogenic activities, is a recipient of several contaminants. Among them, organochlorine pesticides are of major concern, even though they have been banned decades ago in ...
Petros Tsiantas   +3 more
doaj   +1 more source

Level of Organochlorine Pesticide in Prediabetic and Newly Diagnosed Diabetes Mellitus Patients with Varying Degree of Glucose Intolerance and Insulin Resistance among North Indian Population [PDF]

open access: yesDiabetes & Metabolism Journal, 2021
Background Organochlorine pesticides (OCPs) exposure may induce an endocrine disruption which may lead to the risk of developing diabetes through alteration and disturbance of glucose metabolism, insulin resistance, and destruction of β-cells.
Shipra Tyagi   +6 more
doaj   +1 more source

Exposures to pesticides and risk of cancer: Evaluation of recent epidemiological evidence in humans and paths forward

open access: yesInternational Journal of Cancer, Volume 152, Issue 5, Page 879-912, 1 March 2023., 2023
Abstract Knowledge of the role in cancer etiology of environmental exposures as pesticides is a prerequisite for primary prevention. We review 63 epidemiological studies on exposure to pesticides and cancer risk in humans published from 2017 to 2021, with emphasis on new findings, methodological approaches, and gaps in the existing literature.
Haleigh Cavalier   +2 more
wiley   +1 more source

mibPOPdb: An online database for microbial biodegradation of persistent organic pollutants

open access: yesiMeta, Volume 1, Issue 4, December 2022., 2022
This study presents the Microbial Biodegradation of Persistent Organic Pollutants Database (mibPOPdb) database, a web‐accessible literature‐based microbial biodegradation of persistent organic pollutants (POPs) resource. We also developed a robust chemical biodegradability prediction model with Graph Neural Networks.
Tanyaradzwa R. Ngara   +2 more
wiley   +1 more source

The effects of acute toxicity of dieldrin on HeLa Cell Line: An In Vitro assessment

open access: yesInternational Journal of Environmental Health Engineering, 2023
Aim: Among environmental pollutants, there is a great concern about organochlorine pesticides (OCPs) due to their environmental persistence, accumulation in the food chain, detection in breast milk, and their ability to accumulate in adipose tissues. Due
Seyedeh Maryam Sharafi   +5 more
doaj   +1 more source

Functional Pathway Identification with CRISPR/Cas9 Genome Wide Gene Disruption in Human Dopaminergic Neuronal Cells Following Chronic Treatment with Dieldrin.

open access: yesToxicological Sciences, 2020
Organochlorine pesticides, once widely used, are extremely persistent and bio-accumulative in the environment. Epidemiological studies have implicated that environmental exposure to organochlorine pesticides including dieldrin is a risk factor for the ...
Max Russo   +6 more
semanticscholar   +1 more source

Occurrence and distribution of the cyclodiene-type organochlorine pesticides in soils of Vojvodina province, Serbia [PDF]

open access: yesJournal of the Serbian Chemical Society, 2016
Aldrin, endrin and dieldrin are highly toxic and persistent cyclodiene-type organochlorine pesticides. Although these compounds have been banned over the last few decades in many countries, they can still be found in the environment, especially ...
Zeremski Tijana   +5 more
doaj   +1 more source

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