Results 51 to 60 of about 12,893 (251)

Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits

Neurobiology of Disease, 2020
Human and animal studies have shown that exposure to the organochlorine pesticide dieldrin is associated with increased risk of Parkinson's disease (PD).
Aysegul O. Gezer, Joseph Kochmanski, Sarah E. VanOeveren, Allyson Cole-Strauss, Christopher J. Kemp, Joseph R. Patterson, Kathryn M. Miller, Nathan C. Kuhn, Danielle E. Herman, Alyssa McIntire, Jack W. Lipton, Kelvin C. Luk, Sheila M. Fleming, Caryl E. Sortwell, Alison I. Bernstein   +14 more
doaj  

An Interaction of Dieldrin with Thiamine

Experimental Biology and Medicine, 1968
SummaryA dietary level of 20 ppm of dieldrin increased growth in rats raised on rations containing low levels of thiamine, or conversely, the low dietary intake of thiamine produced a smaller growth depression in rats ingesting dieldrin. There was a marked variation among litters in their response to the nutritional stress and the dieldrin produced a ...
openaire   +3 more sources

Homozygous multiple‐insecticide resistance in Australian invasive serpentine leafminer Liriomyza huidobrensis (Blanchard) (Diptera: Agromyzidae)

Austral Entomology, Volume 64, Issue 1, February 2025.
Abstract In October 2020, Liriomyza huidobrensis (serpentine leafminer [SLM]) was first detected in Western Sydney, New South Wales (NSW), and subsequently Southern Queensland (QLD). Control failures were reported, and insecticide resistance was confirmed via bioassay, but mechanisms causing resistance remained unknown.
Yizhou Chen, Duong T. Nguyen, John Webster, Thi Hong Tham Nguyen, Grant A. Herron   +4 more
wiley   +1 more source

Investigating the molecular basis of multiple insecticide resistance in a major malaria vector Anopheles funestus (sensu stricto) from Akaka-Remo, Ogun State, Nigeria

Parasites & Vectors, 2020
Background Understanding the mechanisms used by Anopheles mosquitoes to survive insecticide exposure is key to manage existing insecticide resistance and develop more suitable insecticide-based malaria vector control interventions as well as other ...
Seun M. Atoyebi, Genevieve M. Tchigossou, Romaric Akoton, Jacob M. Riveron, Helen Irving, Gareth Weedall, Eric Tossou, Innocent Djegbe, Isaac O. Oyewole, Adekunle A. Bakare, Charles S. Wondji, Rousseau Djouaka   +11 more
doaj   +1 more source

Differential estrogenic effects of the persistent organochlorine pesticides dieldrin, endosulfan, and lindane in primary neuronal cultures.

Toxicological Sciences, 2011
The organochlorine chemicals endosulfan, dieldrin, and γ-hexachlorocyclohexane (lindane) are persistent pesticides to which people are exposed mainly via diet. Their antagonism of the γ-aminobutyric acid-A (GABA(A)) receptor makes them convulsants.
V. Briz, J. Molina-Molina, S. Sánchez-Redondo, Mariana F. Fernández, J. Grimalt, N. Olea, E. Rodríguez-Farré, C. Suñol   +7 more
semanticscholar   +1 more source

SUSCEPTIBILITY OF ANOPHELES FLUVIATILIS TO INSECTICIDES IN SOUTHERN IRAN [PDF]

Iranian Journal of Public Health, 1982
The first records of Anopheles fluviatilis resistance to DDT was reported in 1963 from India and to dieldrin from eastern Saudi Arabia in 1959. In southern Iran, antimalaria measures began in 1950 and up to 1957 the area was under DDT residual house ...
N.Eshaghy, E.Javadian, A.V.Manouchehri
doaj   +2 more sources

Phenotypic and transcriptomic effects of developmental exposure to nanomolar levels of pesticides in zebrafish

Environmental Advances, 2022
This study investigates the pesticides atrazine, chlorpyrifos, and dieldrin for endocrine disrupting, phenotypic, and neurobehavioral effects. Zebrafish embryos were exposed to various environmentally relevant concentrations of pesticides during two ...
Jessica R. Blount, Jeremiah N. Shields, Chia-Chen Wu, Camille Akemann, Bridget B. Baker, Zoha Siddiqua, Danielle N. Meyer, Nemer Hijazi, Zane Tolbert, David K. Pitts, Tracie R. Baker   +10 more
doaj  

Primates and disability: Behavioral flexibility and implications for resilience to environmental change

American Journal of Primatology, Volume 87, Issue 1, January 2025.
A photo of Nau, a Japanese macaque who was born with one eye, and the key highlights from the review article. Abstract Congenital malformations, conditions, injuries, and illness can lead to long‐term physical impairment and disability in nonhuman primates. How individual primates change their behaviors flexibly to compensate for their disabilities can
Brogan M. Stewart, Megan M. Joyce, Jack Creeggan, Stephanie Eccles, Mikaela G. Gerwing, Sarah E. Turner   +5 more
wiley   +1 more source

Allopregnanolone prevents dieldrin-induced NMDA receptor internalization and neurotoxicity by preserving GABA(A) receptor function.

Endocrinology, 2012
Dieldrin is an endocrine disruptor that accumulates in mammalian adipose tissue and brain. It induces convulsions due to its antagonism of the γ-aminobutyric acid A receptor (GABA(A)R).
V. Briz, J. Parkash, S. Sánchez-Redondo, V. Prévot, C. Suñol   +4 more
semanticscholar   +1 more source

The free energy landscape of GABA binding to a pentameric ligand-gated ion channel and its disruption by mutations [PDF]

arXiv, 2016
Pentameric ligand-gated ion channels (pLGICs) of the Cys-loop superfamily are important neuroreceptors that mediate fast synaptic transmission. They are activated by the binding of a neurotransmitter, but the details of this process are still not fully understood. As a prototypical pLGIC, here we choose the insect resistance to dieldrin (RDL) receptor,
arxiv