The multiple hit model of infantile and epileptic spasms: The 2025 update
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou +6 more
wiley +1 more source
Rapid recovery after intrathecal dexamethasone in FIRES
Epileptic Disorders, EarlyView.
João Filipe Nico +8 more
wiley +1 more source
Ketogenic diet for infantile epileptic spasms
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
Methionine Restriction Alone Induces T-cell-mediated Immunotherapy of Osteosarcoma in a Syngeneic Mouse Model. [PDF]
Mizuta K +9 more
europepmc +1 more source
Abstract Objectives Dravet syndrome (DS) is a drug‐resistant developmental and epileptic encephalopathy, often requiring three or more antiseizure medications (ASMs). Consequently, the therapeutic landscape is highly complex, combining DS‐specific agents (stiripentol, STP; cannabidiol, CBD; fenfluramine, FFA), non‐specific ASMs, and non‐pharmacologic ...
J. Helen Cross +4 more
wiley +1 more source
Small RNA Sequencing of Human Urinary Extracellular Vesicles Reveals Association of High-Sodium Diet With Renal Proinflammatory Pathways. [PDF]
Buffolo F +11 more
europepmc +1 more source
Associations Between Severe Food Insecurity and Food Addiction in Brazilian Low‐Income Women
ABSTRACT Objective The present study aims to assess the distribution of food addiction (FA) across different levels of food insecurity (FI) in Brazilian women of reproductive age living in poverty, and to investigate the association between FA and FI. Method This is a cross‐sectional study conducted between October 2020 and May 2021 in 40 urban favelas
Amanda Ribeiro Berta +7 more
wiley +1 more source
A Comprehensive Analysis of the Impact of Nutrient Intakes on the Stages and Mortality of Cardiovascular-Kidney-Metabolic Syndrome. [PDF]
Qing J +6 more
europepmc +1 more source
ABSTRACT Objective The albumin‐globulin ratio (AGR) is a biochemical marker reflecting nutritional and inflammatory status, with significant prognostic value in chronic conditions. This study examined its association with clinical/biochemical markers in adolescents with anorexia nervosa (AN) and atypical AN (AAN).
Eylem Şerife Kalkan +5 more
wiley +1 more source
The Urgent Need to Harness Public Health Interventions to Tackle the Burden of Cardiovascular Diseases in Africa: Opportunities, Challenges, and Recommendations. [PDF]
Femi-Lawal VO +4 more
europepmc +1 more source

