Results 41 to 50 of about 161,774 (219)

Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis

EMBO Molecular Medicine, 2021
Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment.
Carmen Herranz, Francesca Mateo, Alexandra Baiges, Gorka Ruiz de Garibay, Alexandra Junza, Simon R Johnson, Suzanne Miller, Nadia García, Jordi Capellades, Antonio Gómez, August Vidal, Luis Palomero, Roderic Espín, Ana I Extremera, Eline Blommaert, Eva Revilla‐López, Berta Saez, Susana Gómez‐Ollés, Julio Ancochea, Claudia Valenzuela, Tamara Alonso, Piedad Ussetti, Rosalía Laporta, Antoni Xaubet, José A Rodríguez‐Portal, Ana Montes‐Worboys, Carlos Machahua, Jaume Bordas, Javier A Menendez, Josep M Cruzado, Roser Guiteras, Christophe Bontoux, Concettina La Motta, Aleix Noguera‐Castells, Mario Mancino, Enrique Lastra, Raúl Rigo‐Bonnin, Jose C Perales, Francesc Viñals, Alvaro Lahiguera, Xiaohu Zhang, Daniel Cuadras, Coline H M van Moorsel, Joanne J van der Vis, Marian J R Quanjel, Harilaos Filippakis, Razq Hakem, Chiara Gorrini, Marc Ferrer, Aslihan Ugun‐Klusek, Ellen Billett, Elżbieta Radzikowska, Álvaro Casanova, María Molina‐Molina, Antonio Roman, Oscar Yanes, Miquel A Pujana   +56 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Adherence to the mediterranean diet and risk of hypoglycemia in insulin-treated type 2 diabetic patients

Human Nutrition & Metabolism
Background and aims: Lifestyle intervention, aimed at weight loss and increasing physical activity, is widely known as the first-line treatment in diabetes.
Caterina Formichi, Sonia Caprio, Stefano Auddino, Felicia Rizza, Barbara Paolini, Laura Nigi, Francesco Dotta   +6 more
doaj   +1 more source

Naturopathic Oncology Care for Pediatric Cancers: A Practice Survey

Integrative Cancer Therapies, 2019
Background: The majority of pediatric oncology patients report use of complementary and alternative medicine. Some naturopathic doctors (NDs) provide supportive pediatric oncology care; however, little information exists to formally describe this ...
Athanasios Psihogios ND, Jullie K. Ennis PhD, Dugald Seely ND, MSc, FABNO   +2 more
doaj   +1 more source

Lymphedema and nutrition: A review

Veins and Lymphatics, 2019
Nutrition is considered a basic component in the management of any vascular disease. Lymphedema is characterised by an increase of interstitial fluid due to a lymphatic system morphological and/or functional alteration.
Attilio Cavezzi, Simone Ugo Urso, Lorenzo Ambrosini, Sonia Croci, Fausto Campana, Giovanni Mosti   +5 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Variations in dietary habits during cancer treatment: results of a cross-sectional survey

Acta Clinica Croatica
We aimed to explore variations in dietary habits in cancer patients according to clinical and demographic characteristics. We conducted a cross-sectional survey on cancer patients treated with systemic therapy.
Sana Ennouri, Nouha Daoud, Yosra Berrazegua, Houda El Benna, Sinene Korbi, Haifa Rachdi, Nesrine Mejri, Soumaya Labidi, Hammouda Boussen   +8 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Use of Glycomacropeptide in Dietary Management of Phenylketonuria

Journal of Nutrition and Metabolism, 2016
Dietary therapy is the most common therapy applied in treatment of Phenylketonuria (PKU) with restriction of intake of most natural proteins that are rich in Phenylalanine (Phe).
Osama K. Zaki, Lamia El-Wakeel, Yasmin Ebeid, Hanan S. Ez Elarab, Aisha Moustafa, Nayera Abdulazim, Hala Karara, Ahmed Elghawaby   +7 more
doaj   +1 more source

Administration of Tonsil-Derived Mesenchymal Stem Cells Improves Glucose Tolerance in High Fat Diet-Induced Diabetic Mice via Insulin-Like Growth Factor-Binding Protein 5-Mediated Endoplasmic Reticulum Stress Modulation

Cells, 2019
Type 2 diabetes mellitus (T2DM) is a prevalent chronic metabolic disorder accompanied by high blood glucose, insulin resistance, and relative insulin deficiency.
Younghay Lee, Sun-Hye Shin, Kyung-Ah Cho, Yu-Hee Kim, So-Youn Woo, Han Su Kim, Sung-Chul Jung, Inho Jo, Hee-Sook Jun, Woo-Jae Park, Joo-Won Park, Kyung-Ha Ryu   +11 more
doaj   +1 more source