Results 1 to 10 of about 1,395,174 (227)

A multi-level gene-diet interaction analysis of fish oil and 14 polyunsaturated fatty acid traits identifies the FADS and GPR12 loci [PDF]

open access: yesHGG Advances
Summary: Fish oil supplements (FOS) are known to alter circulating levels of polyunsaturated fatty acids (PUFAs) but in a heterogeneous manner across individuals. These varied responses may result from unidentified gene-FOS interactions.
Susan Adanna Ihejirika   +5 more
doaj   +3 more sources

Selection scan in Native Americans of Mexico identifies FADS2 rs174616: Evidence of gene-diet interactions affecting lipid levels and Delta-6-desaturase activity [PDF]

open access: yesHeliyon
Searching for positive selection signals across genomes has identified functional genetic variants responding to environmental change. In Native Americans of Mexico, we used the fixation index (Fst) and population branch statistic (PBS) to identify SNPs ...
Sandra Romero-Hidalgo   +21 more
doaj   +3 more sources

FALLING FOR FADS? Diagnostic and therapeutic fads in Psychiatry

open access: yesEuropean Psychiatry, 2022
Introduction Psychiatry is not immune to the effects of trends and fads, which are ideas that elicit short-lived enthusiasm, are quickly adopted, and abandoned when they fail to live up to expectations.
S. Jesus   +4 more
doaj   +2 more sources

A supply and demand intervention increased fish consumption among rural women: A randomized, controlled trial. [PDF]

open access: yesPLoS ONE
Malnutrition is a critical public health issue in Timor-Leste, where nearly half of children under five suffer from stunting and diets are chronically low in nutrient-rich foods, including fish.
Alexander Tilley   +8 more
doaj   +2 more sources

Fish and marine fatty acids intakes, the FADS genotypes and long-term weight gain: a prospective cohort study

open access: yesBMJ Open, 2019
Objective We tested whether genetic variants near fatty acid desaturases gene (FADS) cluster, which were recently identified to be signatures of adaptation to fish-rich and n-3 polyunsaturated fatty acids (PUFAs)-rich diet, interacted with these dietary ...
Yoriko Heianza   +20 more
doaj   +2 more sources

Fatty acid desaturase genetic variations in heart failure and cardiovascular disease [PDF]

open access: yesAmerican Heart Journal Plus
Omega (ω)-3 polyunsaturated fatty acids (PUFAs) have gained prominence for their putative cardioprotective functions. However, the data supporting their beneficial effects has been inconsistent.
David Gittess   +4 more
doaj   +2 more sources

Compensatory induction of Fads1 gene expression in heterozygous Fads2-null mice and by diet with a high n-6/n-3 PUFA ratio[S]

open access: yesJournal of Lipid Research, 2016
In mammals, because they share a single synthetic pathway, n-6/n-3 ratios of dietary PUFAs impact tissue arachidonic acid (ARA) and DHA content. Likewise, SNPs in the human fatty acid desaturase (FADS) gene cluster impact tissue ARA and DHA.
Hang Su   +4 more
doaj   +2 more sources

Fad Diets: Facts and Fiction

open access: yesFrontiers in Nutrition, 2022
The global prevalence of obesity is alarmingly high and is impacting both developed and underdeveloped countries, beyond the borders of ethnicity, sex, and age. On the other hand, the global interest in dieting has increased, and people are obsessed with certain fad diets, assuming them as a magic bullet for their long-term problems.
Aaiza Tahreem   +6 more
openaire   +3 more sources

Impact of FADS gene variation and dietary fatty acid exposure on biochemical and anthropomorphic phenotypes in a Hispanic/Latino cohort

open access: yesFrontiers in Nutrition, 2023
IntroductionPolyunsaturated fatty acids (PUFA) and highly unsaturated fatty acid (HUFA) synthetic products and their signaling metabolites play vital roles in immunity, inflammation, and brain development/function.
Susan Sergeant   +7 more
doaj   +1 more source

Substitution analyses of foods with varying fat quality and the associations with all-cause mortality and impact of the FADS-1 genotype in elderly men

open access: yesEuropean Journal of Nutrition, 2023
Purpose To investigate associations between substitutions of foods varying in fat quality and all-cause mortality in elderly Swedish men and to examine effect measure modification by a gene involved in fatty acid desaturation (rs174550 FADS1).
Michael Fridén   +4 more
semanticscholar   +1 more source

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