Results 131 to 140 of about 14,002 (252)

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source

Association of Life's Essential 8 Score With Incident Pancreatic Cancer: A Prospective Cohort Study in Shanghai, China

Cancer Science, EarlyView.
In this prospective cohort study of 60,556 cancer‐free adults with a median follow‐up of 7.44 years, a higher Life's Essential 8 (LE8) score, reflecting better cardiovascular health, was associated with a lower risk of pancreatic cancer (PC). Each 1‐SD increase in LE8 score was associated with an 18% lower PC risk.
Liping Yi, Xing Liu, Maryam Zaid, Kexin Zhang, Biying Wang, Yingqi Deng, Minhua Tang, Yonggen Jiang, Genming Zhao   +8 more
wiley   +1 more source

Input Visualizations to Track Health Data by Older Adults with Multiple Chronic Conditions

Computer Graphics Forum, EarlyView.
Abstract Older adults living with multiple chronic conditions (MCC) can considerably benefit from collecting and reflecting on their health data. Many older adults collect their health data using various approaches, such as digital tools or handwritten notebooks.
Shri Harini Ramesh, Foroozan Daneshzand, Matteo Sotelo, Mahsa Sinaei, Fateme Rajabiyazdi   +4 more
wiley   +1 more source

Cellular Proliferation and Reprogramming in Pre‐Metastatic Niches: Mechanisms and Therapeutic Vulnerabilities

Cell Proliferation, EarlyView.
This review systematically elucidates how primary tumours remotely drive multicellular reprogramming to construct the pre‐metastatic niche and dictate disseminated tumour cell fate. By mapping this dynamic ecosystem, we identify actionable therapeutic vulnerabilities, advocating a paradigm shift from traditional cytotoxicity toward microenvironment ...
Shengqian Wang, Chenghu Song, Pengfei Li, Junjie Feng, Xiaoxuan Shi, Qiwen Lu, Bohan Duan, Xinyan Zhang, Siqi Li, Yang Luo, Xiaohui Fan, Ziyun Li, Yang Zhang, Renjun Gu, Wenjun Mao   +14 more
wiley   +1 more source

Association of Dietary Approaches to Stop Hypertension Diet With the Risk of Osteoporosis and Fracture: A Systematic Review and Meta-Analysis. [PDF]

Food Sci Nutr
Yang B, Hou J, Song X, Zheng S, Deng Q, Xiang R, Zhao X, Qu Y, Sha L, Zhu J, Lei B, Yu T, Han T, Zhou J, Liu T, Xia M, Zhong Y, Pu X, Jiang X.   +18 more
europepmc   +1 more source

Cold plasma treatment for oral lichen planus: a retrospective case collection and proposal of a new clinical score

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Oral lichen planus (OLP) is a chronic autoimmune mucosal disease with malignant potential and limited treatment options. This study evaluated the long‐term efficacy and safety of cold atmospheric plasma (CAP) therapy in therapy‐refractory OLP and introduced the novel Lichen Planus Severity Score (LPSS).
Christian Seebauer, Hans‐Robert Metelmann, Mohamed Falougy, Wolfram Kaduk, Lasse Kremer, Georg Daeschlein   +5 more
wiley   +1 more source

Type 2 diabetes remission following a comprehensive metabolic program including surgery in adults with BMI ≥50 kg/m2 versus BMI <50 kg/m2

Diabetic Medicine, EarlyView.
Abstract Aims Previous reports have suggested that higher baseline BMI (bBMI) or %excess weight loss (EWL) are independent predictors of type 2 diabetes mellitus (T2DM) remission after metabolic bariatric surgery (MBS). However, %EWL appears lower in individuals with bBMI ≥50 kg/m2 than those with lower bBMI.
Xi May Zhen, Annette Macdonald, Benjamin Woodham, Brendan Ryan, Tien‐Ming Hng, Eileene Azar, Marina Hanna, Jesmine Yap, Jeenat Paulose, Guizhi Li, Stephen M. Twigg, Golo Ahlenstiel, Jencia Wong   +12 more
wiley   +1 more source

Mind Your Heart-A Web-Based Dietary Approaches to Stop Hypertension Diet and Mindful Eating Intervention for Working Adults at Elevated Cardiovascular Risk: Pilot Randomized Controlled Trial. [PDF]

JMIR Form Res
Reina AM, Padilla HM, Beer JM, Zhang DS, Renzi-Hammond LM.   +4 more
europepmc   +1 more source

Real‐world observational study evaluating metabolic and kidney outcomes in patients living with chronic kidney disease and type 2 diabetes mellitus with obesity prescribed tirzepatide

Diabetic Medicine, EarlyView.
Abstract Background Obesity and type 2 diabetes mellitus (T2DM) accelerate chronic kidney disease (CKD) progression. Tirzepatide, a dual glucagon‐like peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonist, has demonstrated metabolic and potential renoprotective benefits in clinical trials.
Jack E. Carruthers, Xi Yan Ooi, Dawn Goodall, Jo Reed, Rachna Bedi, Adrian McGrath, Michelle Willicombe, Parizad Avari, Andrew H. Frankel   +8 more
wiley   +1 more source

The dash (dietary approaches to stop hypertension) diet lowers blood lipids [PDF]

American Journal of Hypertension, 2000
openaire   +1 more source