Results 141 to 150 of about 695,687 (261)

Daily caloric restriction limits tumor growth more effectively than caloric cycling regardless of dietary composition. [PDF]

Nat Commun, 2021
Pomatto-Watson LCD, Bodogai M, Bosompra O, Kato J, Wong S, Carpenter M, Duregon E, Chowdhury D, Krishna P, Ng S, Ragonnaud E, Salgado R, Gonzalez Ericsson P, Diaz-Ruiz A, Bernier M, Price NL, Biragyn A, Longo VD, de Cabo R.   +18 more
europepmc   +1 more source

Dietary Control of Skin Lipid Composition and Microbiome [PDF]

Journal of Investigative Dermatology, 2018
Moestrup, Kasper S., Chen, Yun, Schepeler, Troels, Schweiger, Pawel J., Jensen, Kim B.   +4 more
openaire   +3 more sources

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

The microbiome interacts with the circadian clock and dietary composition to regulate metabolite cycling in the <i>Drosophila</i> gut. [PDF]

Elife
Zhang Y, Noya SB, Li Y, Fang J, Sehgal A.   +4 more
europepmc   +1 more source

The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice. [PDF]

BMC Biol, 2021
Zhang Z, Chen X, Loh YJ, Yang X, Zhang C.   +4 more
europepmc   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Estimating the influence of dietary composition and management on nutrient intake and excretion and methane emission in different pig categories. [PDF]

PLoS One
Lashkari S, Dalby FR, Krogh U, Sattarova E, Børsting CF.   +4 more
europepmc   +1 more source

Differences in dietary composition and preference maintained despite gene flow across a woodrat hybrid zone. [PDF]

Ecol Evol, 2021
Nielsen DP, Matocq MD.
europepmc   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Pilot and feasibility study of dietary composition with elexacaftor-tezacaftor-ivacaftor concentrations in people with cystic fibrosis. [PDF]

Pharmacotherapy
Rose NR, Bailey J, Anderson JD, Chalamalla AR, Ryan KJ, Acosta EP, Guimbellot JS.   +6 more
europepmc   +1 more source