Results 161 to 170 of about 1,664,645 (330)

Mitochondrial Transplantation Augments the Reparative Capacity of Macrophages Following Myocardial Injury

open access: yesAdvanced Science, EarlyView.
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang   +10 more
wiley   +1 more source

Dietary Fat and Androgens [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 2005
openaire   +3 more sources

Intestinal lipid-derived signals that sense dietary fat.

open access: yesJournal of Clinical Investigation, 2015
N. DiPatrizio, D. Piomelli
semanticscholar   +1 more source

Disruption of Gut Microbiota‐Mediated De Novo NAD+ Synthesis Contributes to the Development of Polycystic Ovary Syndrome

open access: yesAdvanced Science, EarlyView.
This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen   +6 more
wiley   +1 more source

The source of dietary fat influences anti-tumour immunity in obese mice. [PDF]

open access: yesNat Metab
Kunkemoeller B   +29 more
europepmc   +1 more source

The 2015 US Dietary Guidelines: Lifting the Ban on Total Dietary Fat.

open access: yesJournal of the American Medical Association (JAMA), 2015
D. Mozaffarian, D. Ludwig
semanticscholar   +1 more source

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

open access: yesAdvanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou   +14 more
wiley   +1 more source

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