Results 121 to 130 of about 895,689 (285)

Neonatal Exposure to Antibiotics Triggers Obesity in Adulthood by Permanent Microbiota Dysbiosis and Reduction of Adipose Regulatory T Cells

Barrier Immunity, EarlyView.
ABSTRACT Neonatal dysbiosis of the gut microbiota represents a critical environmental factor promoting obesity, but the underlying immunological mechanisms remain unknown. We show here that neonatal treatment of mice with broad‐spectrum antibiotics for the first 3 weeks of life (NeoATB) resulted in the development of obesity and metabolic abnormalities
Peter Zanvit, Junji Xu, Wenjing Yang, Nancy Guo, Tianming Yu, Xue Jiao, Michaela Prochazkova, Wenwen Jin, Na Liu, Sang‐A Park, Cheryl Chia, Daxesh P. Patel, Dunfang Zhang, Nathan Goldberg, Alexander Cain, Frank J. Gonzalez, Yasmine Belkaid, Yingzi Cong, WanJun Chen   +18 more
wiley   +1 more source

Integrative Omics Analysis Reveals a CD206+ Macrophage/Dendritic Cell–CD155–TIGIT+ Regulatory T Cell Axis as a Protective Immune Checkpoint Pathway in Atherosclerosis Progression

Barrier Immunity, EarlyView.
ABSTRACT RNA sequencing (RNA‐seq) analysis revealed transcriptional features indicative of sustained immunosuppression within regulatory T cells (Tregs) isolated from atherosclerotic tissues, highlighting the critical contribution of immune checkpoint (ICP) receptor–ligand interactions to atherosclerosis progression. To comprehensively characterize the
Ying Shao, Fatma Saaoud, Mohammed Ben Issa, Keman Xu, Yifan Lu, Shih‐Yu Hung, Juanjuan Liu, Bo Yuan, Juncheng Wei, Sheng Wu, Sadia Mohsin, Zhengjie Zhou, Beata Kosmider, Laisel Martinez, Roberto Vazquez‐Padron, Hong Wang, Xiaofeng Yang   +16 more
wiley   +1 more source

Dietary potassium restriction in chronic kidney disease

An integrative narrative review of evidence, uncertainty and practice persistence Background: Dietary potassium restriction is a routine part of chronic kidney disease care and is commonly used ...
Andrew Morris
core   +1 more source

Perceptions of hemodialysis patients about dietary and fluid restrictions

Brazilian Journal of Nephrology
Introduction: Dietary regimen for hemodialysis (HD) patients is complicate and identifying characteristics and reasons of those most likely to experience difficulty in adhering to dietary restrictions is important.
Fabiana Baggio Nerbass, Dyane Correa, Rafaela G. dos Santos, Tatiana S. Kruger, Andrea C. Sczip, Marcos A. Vieira, Jyana G. Morais   +6 more
doaj   +1 more source

Low‐Dimensional Materials and Van Der Waals Heterostructures for Energy Application: A Comprehensive Review

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Low‐dimensional materials (0D, 1D, and 2D) exhibit unique electronic and physicochemical properties, enabling advanced nanoelectronic and optoelectronic devices. Mixed‐dimensional heterostructures combine these materials to enhance functionality.
Qaisar Alam, Sajjad Ali, Pir Muhammad Ismail, ABM Sharif Hossain   +3 more
wiley   +1 more source

Deletion of Kir5.1 Impairs Renal Ability to Excrete Potassium During Increased Dietary Potassium Intake

, 2019
BACKGROUND: The basolateral potassium channel in the distal convoluted tubule (DCT), comprising the inwardly rectifying potassium channel Kir4.1/Kir5.1 heterotetramer, plays a key role in mediating the effect of dietary potassium intake on the thiazide ...
Wang, Wen-Hui, Lin, Dao-Hong, Zhang, Dan-Dan, Gao, Zhong-Xiuzi, Wu, Peng, Su, Xiao-Tong   +5 more
core   +1 more source

Potassium supplementation and depletion during development of salt-sensitive hypertension in male and female SS rats

JCI Insight
The dietary sodium/potassium ratio is positively correlated with blood pressure, and understanding this relationship is crucial for improving hypertension treatment. Moreover, few studies have examined these effects in both sexes. In this study, we aimed
Adrian Zietara, Lashodya V. Dissanayake, Melissa Lowe, Biyang Xu, Vladislav Levchenko, Vasundhara Kain, Ganesh V. Halade, Christine A. Klemens, Oleg Palygin, Alexander Staruschenko   +9 more
doaj   +1 more source

Estimation of Dietary Exposure to Sodium Benzoate (E211) and Potassium Sorbate (E202) of Children and Adolescents in the Oran Region, Algeria

Foods
Sodium benzoate (E211) and potassium sorbate (E202) are two preservatives widely used alone or in combination in the food industry in Algeria. This study aims to estimate the dietary exposure of children and adolescents to these substances in Oran ...
Fatima Saida Zouaoui, Rachid Boukhari, Nabila Heroual, Nadjette Djemouai, Dalal Redouane, Djamel Saidi, Samia Addou, Omar Kheroua   +7 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source