Results 131 to 140 of about 41,482 (195)

Associating diethylhexyl phthalate to gestational diabetes mellitus via adverse outcome pathways using a network-based approach

Science of the Total Environment, 2022
Gestational diabetes mellitus (GDM) is a common pregnancy complication that is harmful to both the woman and fetus. Several epidemiological studies have found that exposure to diethylhexyl phthalate (DEHP), an endocrine disruptor ubiquitous in the ...
An Zhu
exaly   +2 more sources

Prenatal and breastfeeding exposure to low dose of diethylhexyl phthalate induces behavioral deficits and exacerbates oxidative stress in rat hippocampus

Food and Chemical Toxicology, 2021
Diethylhexyl phthalate (DEHP) is one of the most important derivatives of phthalate that has devastating effects on nervous system function. In this study, the effects of exposure with low doses of DEHP during pregnancy and lactation periods have been ...
Maryam Ghasemi-Kasman, Farideh Feizi, Ebrahim Zabihi   +2 more
exaly   +2 more sources

Effects of cadmium and diethylhexyl phthalate on skin microbiota of Rana chinensis tadpoles

Environmental Science and Pollution Research, 2023
Skin microbiotas play a crucial role in the health, homeostasis, and immune function of amphibians. The contaminants in water could affect the structure and composition of microbial communities. The effects of coexisting pollutants on frogs cannot be adequately explained by a single exposure due to the coexistence of Cd and DEHP in the environment ...
Zhaoyang Jiang, Yujia Shen, Ziyi Niu, Xinyi Li   +3 more
openaire   +3 more sources

Diethylhexyl phthalate induces immune dysregulation and is an environmental immune disruptor

Journal of Hazardous Materials
Diethylhexyl phthalate (DEHP) is the most abundant phthalate compound in the environment, and has been linked with multiple human diseases. The immune system is closely associated with the occurrence and progression of various diseases. However, minimal research has addressed the impact of DEHP on the immune system.
Dongli, Linghu, Zhenru, Zhu, Dongyan, Zhang, Yongyi, Luo, Jing, Ma, Tao, Li, Zhichao, Sun, Zheng, Xie, Jingyuan, Sun, Chuanhui, Cao   +9 more
openaire   +3 more sources

Diethylhexyl Phthalate and Bisphenol A Promote Vincristine and Tamoxifen Resistancein Vitro

Chemical Research in Toxicology, 2022
Environmental estrogen active compounds are strong determinants of estrogen receptor (ER)-positive breast cancers, and increased evidence indicates their contribution to chemotherapy resistance. In the current study, the efficacy of vincristine and tamoxifen, with the presence of diethylhexyl phthalate (DEHP) and bisphenol A (BPA) and the possible ...
Recep Uyar, Begum Yurdakok-Dikmen, Yagmur Turgut, Ayhan Filazi   +3 more
openaire   +3 more sources

Migration of diethylhexyl phthalate from PVC bags into intravenous cyclosporine solutions

Journal of Pharmaceutical and Biomedical Analysis, 2005
The migration of diethylhexyl phthalate (DEHP) from PVC bags into LVPS (0.9% NaCl) and LVPS with cyclosporine at concentrations of 2.5 and 0.5mg/ml was studied. PVC bags were placed in contact with these solutions and stored at 25+/-1 degrees C. They were taken for analysis each 30 min during 6 h and after this period at each 1 h until 12 h of contact.
Gotardo, M. A., Monteiro, Magali
exaly   +4 more sources

Hazard to the developing male reproductive system from cumulative exposure to phthalate esters—dibutyl phthalate, diisobutyl phthalate, butylbenzyl phthalate, diethylhexyl phthalate, dipentyl phthalate, and diisononyl phthalate

Regulatory Toxicology and Pharmacology, 2009
Phthalate esters are found in a wide variety of consumer and food packing products. Hence there is widespread exposure of the human population to these chemicals. Some of the phthalate esters are known to be toxic to the developing male reproductive system.
exaly   +3 more sources

Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis

Toxicology, 2006
Diethylhexyl phthalate (DEHP) is widely used as a plasticizer in consumer products and is known to disturb the development of the male reproductive system in rats. The mechanisms by which DEHP exerts these effects are not yet fully elucidated, though some of the effects are related to reduced fetal testosterone production.
Leon J S Brokken, Anne Marie Vinggaard
exaly   +3 more sources

Leaching of diethylhexyl phthalate from polyvinyl chloride bags into intravenous etoposide solution

Journal of Clinical Pharmacy and Therapeutics, 2002
To compare the release of diethylhexyl phthalate (DEHP) from polyvinyl chloride (PVC) bags from four different manufacturers into intravenous etoposide solutions.Etoposide solutions, 0.4 mg/mL, containing the vehicle polysorbate 80 were prepared in 5% dextrose or 0.9% sodium chloride injection PVC bags and stored at room temperature for 24 h.
B, Demoré, J, Vigneron, A, Perrin, M A, Hoffman, M, Hoffman   +4 more
exaly   +3 more sources