Results 201 to 210 of about 4,151,021 (263)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The impact of DRG payment reform on stroke inpatient costs: a propensity score matching and difference-in-differences analysis of a large public hospital in Northeast China. [PDF]

BMC Public Health
Gao L, Li R, Cheng H, Dong X, Liu Y, Tian R, Zhang T, Guo B.   +7 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Income Inequality and Self-Reported Health: A Difference-in-Differences Study. [PDF]

J Prim Care Community Health
Adegoke K.
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Effect of medical insurance policy on child health indicators: an empirical test of difference-in-differences model. [PDF]

Front Public Health
Luo H, Fu J, Xiao M.
europepmc   +1 more source

A difference-in-differences analysis of Medicaid expansion and state paid sick leave laws on colorectal cancer screening. [PDF]

Cancer
Stimpson JP, Liao JM, Morenz AM, Joo JH, Wilson FA.   +4 more
europepmc   +1 more source

Insurance coverage and employment after Medicaid expansion with work requirements: quasi-experimental difference-in-differences study.

BMJ
Johnson DY, Mein SA, Marinacci LX, Liu M, Wadhera RK.   +4 more
europepmc   +1 more source

The Causal Relationship Between Long-Term Exposure to Major PM_2.5 Constituents and the Rate of Emergency Department Visits: A Difference-in-Differences Study. [PDF]

Toxics
Zhao P, Xie C, Wang S, Lin S, Dong G, Li J, Yu S, Zhang T, Yu X, Lin X, Li S, Wu X, Zhou J, Zhang W.   +13 more
europepmc   +1 more source

Association Between a Co-Designed Dashboard and Use of Costly Health Services in Patients With Chronic Kidney Disease and Advanced Cancer: Propensity Score-Adjusted Difference-in-Differences Study. [PDF]

J Med Internet Res
Amagai S, Harris A, Mohindra N, Kircher S, Linder JA, Aggarwal V, Peipert JD, Bedjeti K, Mai Q, Barnard C, Coughlin A, O'Connor M, Morken V, Cella D, Jordan N.   +14 more
europepmc   +1 more source