Results 281 to 290 of about 12,640,589 (322)

Influence of physical exercise on activities of daily living in older adults: an empirical analysis based on propensity score matching and difference-in-differences. [PDF]

Front Public Health
Ma X, Li X, Che L, Dong J.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The Impact of a New Case-Based Payment System on Quality of Care: A Difference-in-Differences Analysis in China. [PDF]

Risk Manag Healthc Policy
Zhang X, Qian M, Yan J, Wang R, Lyu D, Ying X, Tang S.   +6 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

MRTP claim authorisation and General Snus sales in the USA: evidence from a difference-in-differences model. [PDF]

Tob Control
Liber AC, Seidenberg AB, Pesko MF.
europepmc   +1 more source

Crisis response in Texas youth impacted by Hurricane Harvey: A difference-in-differences analysis. [PDF]

J Affect Disord
Williamson T, Sugg MM, Singh D, Green S, Runkle JD.   +4 more
europepmc   +1 more source

The Impact of Armed Conflict in Northern Nigeria on Reproductive Autonomy and Unmet Need for Family Planning: A Difference-in-Differences Propensity Score Matching Approach. [PDF]

Health Sci Rep
Vilier L, Groot W.
europepmc   +1 more source

The impact of the centralized volume-based procurement policy on Chinese pharmaceutical manufacturing firms' R&D investment: A difference-in-differences approach. [PDF]

PLoS One
Qiu F, Chen S, Li Y, Wang X, Zhu M.
europepmc   +1 more source

Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis. [PDF]

BMC Public Health
Tong X, Zou H, Zhang L, Chen W.
europepmc   +1 more source

Validation of a Difference-in-Differences Investigation Tool (DiD IT) for quantifying local outbreaks

Morbey R, Charlett A, Todkill D, Elliot AJ.   +3 more
europepmc   +1 more source