Results 121 to 130 of about 2,744,037 (263)
Difference-in-differences (DiD) is one of the most popular approaches for empirical research in economics, political science, and beyond. Identification in these models is based on the conditional parallel trends assumption: In the absence of treatment, the average outcome of the treated and untreated group are assumed to evolve in parallel over time ...
Bach, Philipp +4 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Discover SustainabilityClimate change is a pressing global challenge that requires collaborative efforts to address the associated uncertainty. This research investigates the impact of climate policy uncertainty (CPU) on digital transformation among 4848 Chinese A-share listed
Xiaohang Ren +4 more
doaj +1 more source
Distributional Difference-in-Differences Models with Multiple Time Periods
Researchers are often interested in evaluating the impact of a policy on the entire (or specific parts of the) distribution of the outcome of interest. In this paper, I provide a method to recover the whole distribution of the untreated potential outcome for the treated group in non-experimental settings with staggered treatment adoption by ...
openaire +2 more sources
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
[Differently abled: difference and the historical model of the standard man].
Historia, ciencias, saude--Manguinhos, 2010 The article offers a critical analysis of how the differences displayed by people with disabilities have been perceived and dealt with in the social, educational, political, and therapeutic realms from ancient times until recent decades, when changes have been observed in Brazil.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Romanian Economic JournalThis research investigates the economic impacts of European Union (EU) membership using the Difference-in-Differences model. The study systematically analyzes data from multiple countries and time periods to determine how joining the EU influences ...
Mircea Diavor
doaj
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source