Results 101 to 110 of about 357,123 (287)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

FACTPLA: Functional analysis and the complexity of testing programmable logic array [PDF]

open access: yes, 1988
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.A computer aided method for analyzing the testability of Programmable Logic Arrays (PLAs) is described.
Abbas, Samir I
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Co-ordination and public administration in a global economy — A Hungarian point of view [PDF]

open access: yes, 2009
The purpose of social co-ordination mechanisms is to co-ordinate the activities of individuals and organisations specialised in the distribution of work.
Attila Chikán, Chikán, Attila
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Grid-connected photovoltaic module and array sizing based on an iterative approach [PDF]

open access: yes, 2014
This paper deals with the sizing of a simple but efficient grid-connected photovoltaic (GCPV) system to minimize the difference between the electrical energy generated by the GCPV system and the required energy.
Rotaru, M.   +2 more
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

A Three-Dimensional Imaging Method for Unmanned Aerial Vehicle-Borne SAR Based on Nested Difference Co-Arrays and Azimuth Multi-Snapshots

open access: yesRemote Sensing
Due to its miniature size and single-pass nature, Unmanned Aerial Vehicle (UAV)-borne array synthetic aperture radar (SAR) is capable of obtaining three-dimensional (3D) electromagnetic scattering information with a low cost and high efficiency, making ...
Ruizhe Shi   +4 more
doaj   +1 more source

Review on Nested Array Design Research [PDF]

open access: yesHangkong bingqi
Array signal processing is an important branch of signal processing, which is widely used in radar, sonar and wireless communication. Direction of arrival estimation, as one of its key applications, traditionally relies on the layout of uniform linear ...
Mao Yanyuan, Ma Wanyu, Si Weijian
doaj   +1 more source

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