Results 181 to 190 of about 793,794 (302)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Reinvestigation of Absorption Spectroscopic Thermal Dynamics of Archaerhodopsin 3 Based Voltage Sensor QuasAr1. [PDF]

Bioengineering (Basel)
Penzkofer A, Silapetere A, Hegemann P.
europepmc   +1 more source

A Study of Global Dynamics and Oscillatory Behavior of Rational-Type Nonlinear Fuzzy Difference Equations with Exponential Decay [PDF]

Sara Saud, Carlo Cattani, Muhammad Tanveer, Muhammad Usman, Asifa Tassaddiq   +4 more
openalex   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Analysis of inverse problem for pseudo-hyperbolic equation under periodic boundary condition. [PDF]

Sci Rep
Bağlan İ, Yernazar A, Aslan E, Budak H, Vivas-Cortez M.   +4 more
europepmc   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Tutorial on Causal Mediation Analysis for Pharmacometricians. [PDF]

CPT Pharmacometrics Syst Pharmacol
Goulooze SC, Marostica E, Snelder N.
europepmc   +1 more source

Asymptotics of a Steady-State Condition of Finite-Difference Approximation of a Logistic Equation with Delay and Small Diffusion

, 2015
S. A. Kaschenko, Valentin Frolov
openalex   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Behavior of Electrothermal Actuator Analyzed by Polynomial Point Interpolation Collocation Method. [PDF]

Micromachines (Basel)
Tang Y, Qi A, Gu Y, Zhu Y, Li H, Gu D, Chen H.   +6 more
europepmc   +1 more source