Results 41 to 50 of about 3,579,879 (270)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Solutions of the Rational Difference Equations

open access: yesMANAS: Journal of Engineering, 2018
Inthis paper the solutions of the following difference equation is examined, (1) wherethe initial conditions are positive real numbers.
Peil Esengul Kyzy, Dagıstan Şimşek
doaj  

Moduli spaces of d-connections and difference Painleve equations [PDF]

open access: yes, 2006
We show that difference Painleve equations can be interpreted as isomorphisms of moduli spaces of d-connections on the projective line with given singularity structure. We also derive a new difference equation.
Arinkin, D., Borodin, A.
core  

Existence results to a nonlinear p(k)-Laplacian difference equation

open access: yes, 2017
In the present paper, by using variational method, the existence of non-trivial solutions to an anisotropic discrete non-linear problem involving p(k)-Laplacian operator with Dirichlet boundary condition is investigated.
Avci, Mustafa, Moghadam, Mohsen Khaleghi
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

On a Higher-Order Nonlinear Difference Equation

open access: yesAbstract and Applied Analysis, 2010
This paper shows that all positive solutions of a higher-order nonlinear difference equation are bounded, extending some recent results in the literature.
Bratislav D. Iričanin
doaj   +1 more source

Solvability of some classes of nonlinear first-order difference equations by invariants and generalized invariants

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2019
We introduce notion of a generalized invariant for difference equations, which naturally generalizes notion of an invariant for the equations. Some motivations, basic examples and methods for application of invariants in the theory of solvability of ...
Stevo Stevic
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

On the Difference Equation xn=anxn-k/(bn+cnxn-1⋯xn-k)

open access: yesAbstract and Applied Analysis, 2012
The behavior of well-defined solutions of the difference equation xn=anxn-k/(bn+cnxn-1⋯xn-k), n∈ℕ0, where k∈ℕ is fixed, the sequences an, bn and cn are real, (bn,cn)≠(0,0), n∈ℕ0, and the initial values x-k,…,x-1 are real numbers, is described.
Stevo Stević   +3 more
doaj   +1 more source

General solutions to four classes of nonlinear difference equations and some of their representations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2019
We present general solutions to four classes of nonlinear difference equations, as well as some representations of the general solutions for two of the classes in terms of specially chosen solutions to linear homogeneous difference equations with ...
Stevo Stevic
doaj   +1 more source

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