Results 41 to 50 of about 844,096 (267)

Conservative Finite-Difference Scheme for 1D Ginzburg–Landau Equation

open access: yes, 2022
In this study, our attention is focused on deriving integrals of motion (conservation laws; invariants) for the problem of an optical pulse propagation in an optical fiber containing an optical amplifier or attenuator because, to date, such invariants ...
Yongqiang Yang   +5 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

On a Higher‐Order Difference Equation

open access: yesDiscrete Dynamics in Nature and Society, 2010
We describe in an elegant and short way the behaviour of positive solutions of the higher‐order difference equation xn = cxn−pxn−p−q/xn−q, n ∈ ℕ0, where p, q ∈ ℕ and c > 0, extending some recent results in the literature.
Bratislav D. Iričanin, Wanping Liu
openaire   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Global behavior of a third order rational difference equation [PDF]

open access: yes, 2006
summary:In this paper, we determine the forbidden set and give an explicit formula for the solutions of the difference equation $$x_{n+1}=\frac {ax_{n}x_{n-1}}{-bx_{n}+ cx_{n-2}},\quad n\in \mathbb {N}_0 $$ where $a$, $b$, $c$ are positive real numbers ...
Aloqeili, Marwan, Abo-Zeid, Raafat
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

On the local dynamics of polynomial difference equations with fading stochastic perturbations

open access: yes, 2010
We examine the stability-instability behaviour of a polynomial difference equa- tion with state-independent, asymptotically fading stochastic perturbations. We find that the set of initial values can be partitioned into a stability region, an instability
Kelly, C.   +3 more
core  

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