Results 71 to 80 of about 3,579,879 (270)

Stability analysis for a rational difference equation

open access: yesArab Journal of Basic and Applied Sciences, 2020
Most qualitative behaviours of difference equations are rapidly investigated nowadays. This can be attributed to the fact that it is often sophisticated to construct the exact solutions of most difference equations. This article is written to analyse the
M. B. Almatrafi, Marwa M. Alzubaidi
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

On A System of Rational Difference Equation

open access: yesDemonstratio Mathematica, 2014
In this paper, we study local asymptotic stability, global character and periodic nature of solutions of the system of rational difference equations given by xn+1= , yn=, n=0, 1,…, where the parameters a; b; c; d; e; f ∊ (0; ∞), and with initial ...
Din Qamar
doaj   +1 more source

From differential to difference equations for first order ODEs [PDF]

open access: yes
When constructing an algorithm for the numerical integration of a differential equation, one should first convert the known ordinary differential equation (ODE) into an ordinary difference equation.
Freed, Alan D., Walker, Kevin P.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Note on the binomial partial difference equation

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2015
Some formulas for the "general solution" to the binomial partial difference equation $$c_{m,n}=c_{m-1,n}+c_{m-1,n-1},$$ are known in the literature. However, it seems that there is no such a formula on the most natural domain connected to the equation ...
Stevo Stevic
doaj   +1 more source

Analytical Solution to a Third-Order Rational Difference Equation. [PDF]

open access: yesScientificWorldJournal, 2023
Salas S AH   +2 more
europepmc   +1 more source

An Ap\'ery-like difference equation for Catalan's constant

open access: yes, 2002
Applying Zeilberger's algorithm of creative telescoping to a family of certain very-well-poised hypergeometric series involving linear forms in Catalan's constant with rational coefficients, we obtain a second-order difference equation for these forms ...
Zudilin, Wadim
core   +5 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

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