Results 71 to 80 of about 4,949,896 (284)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

p-adic difference-difference Lotka-Volterra equation and ultra-discrete limit

International Journal of Mathematics and Mathematical Sciences, 2001
We study the difference-difference Lotka-Volterra equations in p-adic number space and its p-adic valuation version. We point out that the structure of the space given by taking the ultra-discrete limit is the same as that of the p-adic valuation space ...
Shigeki Matsutani
doaj   +1 more source

The Form of the Solutions of System of Rational Difference Equation

Journal of Mathematical Sciences and Modelling, 2018
In this article, we study the form of the solutions of the system of difference equations $x_{n+1}=((y_{n-8})/(1+y_{n-2}x_{n-5}y_{n-8}))$, $y_{n+1}=((x_{n-8})/(\pm1\pm x_{n-2}y_{n-5}x_{n-8}))$, with the initial conditions are real numbers.
E. M. Elsayed, Marwa M. Alzubaidi
doaj   +1 more source

On The Recursive Sequence x(n+1)=x(n-20)/[1+x(n-2)x(n-5)x(n-8)x(n-11)x(n-14)x(n-17)]

MANAS: Journal of Engineering, 2019
The behaivour of the solutions of the following system ofdifference equations is examined,x(n+1)=x(n-20)/[1+x(n-2)x(n-5)x(n-8)x(n-11)x(n-14)x(n-17)]where the initial conditions are positive real numbers.The initial conditions of the equation are ...
Burak Oğul, Dağıstan Şimşek
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

On A System of Rational Difference Equation

Demonstratio Mathematica, 2014
In this paper, we study local asymptotic stability, global character and periodic nature of solutions of the system of rational difference equations given by xn+1= , yn=, n=0, 1,…, where the parameters a; b; c; d; e; f ∊ (0; ∞), and with initial ...
Din Qamar
doaj   +1 more source

Stability analysis for a rational difference equation

Arab Journal of Basic and Applied Sciences, 2020
Most qualitative behaviours of difference equations are rapidly investigated nowadays. This can be attributed to the fact that it is often sophisticated to construct the exact solutions of most difference equations. This article is written to analyse the
M. B. Almatrafi, Marwa M. Alzubaidi
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Eigenvalue problems for a conjugate difference equation

, 2010
We consider the third order difference equation ∆^3 y(k)+λF(k,y,∆y,∆^2y)=02≤k≤T+3 satisfying conjugate boundary conditions y(0)=y(1)=y(T+3)=0 Values of λ are characterized so that the boundary value problem has a positive solution ...
Chyan, Chuan-jen; 錢傳仁; Henderson, J.
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source