Results 71 to 80 of about 804,394 (262)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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On Invariants for Difference Equations and Systems of Difference Equations of Rational Form
Journal of Mathematical Analysis and Applications, 1999 The author generalizes results of \textit{C. J. Schinas} [J. Math. Anal. Appl. 216, No. 1, 164-179 (1997; Zbl 0889.39006)] on invariants of difference equations of rational form to second- and third-order autonomous and nonautonomous difference equations.
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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Global Stability of a Rational Difference Equation
Discrete Dynamics in Nature and Society, 2010 We consider the higher-order nonlinear difference equation 𝑥𝑛+1=(𝑝+𝑞𝑥𝑛−𝑘)/(1+𝑥𝑛+𝑟𝑥𝑛−𝑘),𝑛=0,1,… with the parameters, and the initial conditions 𝑥−𝑘,…,𝑥0 are nonnegative real numbers.
Guo-Mei Tang, Lin-Xia Hu, Gang Ma
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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Oscillatory properties for Emden–Fowler type difference equations with oscillating coefficients
Results in Applied MathematicsIn this paper, we give new criteria on the oscillation of the fourth-order Emden–Fowler type delay difference equation with oscillating coefficients of the form ΔWn+rnyn−τβ=0,n≥n0,where Wn=pnΔ3vnα and vn=yn+qnyn−σ.
Yaşar Bolat +2 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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