Results 101 to 110 of about 380,567 (310)
Book Review: Ordinary difference-differential equations [PDF]
F. H. Brownell
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Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
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Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
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Analytic theory of linear q-difference equations [PDF]
W. J. Trjitzinsky
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On Invariants for Difference Equations and Systems of Difference Equations of Rational Form
The author generalizes results of \textit{C. J. Schinas} [J. Math. Anal. Appl. 216, No. 1, 164-179 (1997; Zbl 0889.39006)] on invariants of difference equations of rational form to second- and third-order autonomous and nonautonomous difference equations.
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In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
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Formal theory of irregular linear difference equations [PDF]
George D. Birkhoff
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Invariants for Difference Equations and Systems of Difference Equations of Rational Form
The author consideres the system of difference equations \[ x_{n+1} = \frac{a_n y_n + A}{x_{n-1}}, \qquad y_{n+1} = \frac{b_n x_n + A}{y_{n-1}}, n = 0, 1,\dots\tag{1} \] where the coefficients \(\{a_n\}\) and \(\{b_n\}\) are periodic sequences of positive numbers of period 2 and \(A\) is a positive constant. Some invariants for system (1) are presented.
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Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
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