Results 101 to 110 of about 4,636,999 (250)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
On Two Systems of Difference Equations
Discrete Dynamics in Nature and Society, 2010 We give very short and elegant proofs of the main results in the work of Yalcinkaya et al. (2008).
Bratislav Iričanin, Stevo Stević
doaj +1 more source
Threshold dynamics of difference equations for SEIR model with nonlinear incidence function and infinite delay. [PDF]
Eur Phys J Plus, 2021 Bentout S +3 more
europepmc +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
INITIAL AND BOUNDARY VALUE PROBLEMS FOR DIFFERENCE EQUATIONS [PDF]
We consider initial and boundary value problems for linear nonhomogeneous difference equations with constant coefficients. For such problems we compute the numerical values of the solutions using the discrete deconvolution.
Mircea I CÎRNU
core
Oscillation of certain partial difference equations
Discrete Dynamics in Nature and Society, 1998 We first obtain sufficiency conditions for the oscillation of all solutions of linear partial difference equation aAm+1,n+1+bAm+1,n+cAm,n+1−dAm,n+Pm,nAm−k,n−1=0.
Sung Kyu Choi, Bing Gen Zhang
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Periodic solutions of whole line difference equations,
, 2004 Periodicity of the solutions of whole line difference equations is investigated. The considered equations is linear and of convolution type.
Russo E, Vecchio A, Crisci MR
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