Results 101 to 110 of about 1,304,903 (278)

Optimal Difference Operator Selection [PDF]

, 2008
Differential operators are essential in many image processing applications. Previous work has shown how to compute derivatives more accurately by examining the image locally, and by applying a difference operator which is optimal for each pixel neighborhood.
Peter Veelaert, Kristof Teelen
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

An Approach to Multidimensional Discrete Generating Series

Mathematics
We extend existing functional relationships for the discrete generating series associated with a single-variable linear polynomial coefficient difference equation to the multivariable case.
Svetlana S. Akhtamova, Tom Cuchta, Alexander P. Lyapin   +2 more
doaj   +1 more source

On Correctness of Cauchy problem for a Polynomial Difference Operator with Constant Coefficients

Известия Иркутского государственного университета: Серия "Математика", 2018
The theory of linear difference equations is applied in various areas of ma\-the\-matics and in the one-dimensional case is quite established. For $n>1$, the situation is much more difficult and even for the constant coefficients a general description of
M. S. Apanovich, E.K. Leinartas
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Generalized Du Fort-Frankel methods for parabolic initial boundary value problems [PDF]

The Du Fort-Frankel difference scheme is generalized to difference operators of arbitrary high order accuracy in space and to arbitrary order of the parabolic differential operator. Spectral methods can also be used to approximate the spatial part of the
Gottlieb, D., Gustafsson, B.
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A fractal-fractional gingerbread-man map generalized by p−fractal-fractional difference operator

Қарағанды университетінің хабаршысы. Математика сериясы
By using the generalization of the gamma function (p−gamma function: Γp(.)), we introduce a generalization of the fractal-fractional calculus which is called p−fractal-fractional calculus. Examples are illustrated including the basic power functions. As
R.W. Ibrahim, S. Momani
doaj   +1 more source

Difference Krichever-Novikov operators

, 2014
In this paper we study commuting difference operators of rank two. We introduce an equation on potentials $V(n),W(n)$ of the difference operator $L_4=(T+V(n)T^{-1})^2+W(n)$ and some additional data. With the help of this equation we find the first examples of commuting difference operators of rank two corresponding to spectral curves of higher genus.
Mauleshova, Gulnara S., Mironov, Andrey E.   +1 more
openaire   +2 more sources