Results 171 to 180 of about 3,332 (213)
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
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Difference Analog of the Lamé Operator
Proceedings of the Steklov Institute of MathematicszbMATH Open Web Interface contents unavailable due to conflicting licenses.
A E Mironov
exaly +3 more sources
Difference Operators on Fuzzy Sets
International Journal of Approximate ReasoningzbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bo Wen Fang
exaly +3 more sources
On Difference Operators and their Factorization
Canadian Journal of Mathematics, 1983Throughout this paper A will be used to denote a given set and g a permutation of it. We shall assume that there is a subset C ⊆ A so that1Here Z denotes the set of integers. For x ∈ A it now follows that there is an unique α(x) ∈ Z so that2and then alsoIn general we shall be concerned with solving the following equation for u3where pi, n ≤ i ≤ r, and ...
Browne, Patrick J., Nillsen, R. V.
openaire +2 more sources
Difference sets and inverting the difference operator
Combinatorica, 1996For \(A\subseteq N_0\) let \(D(A)\) be the set of differences of elements of \(A\) in \(N_0\). Problem: study equations \(D^k(X)=B\). There is a solution if \(0\in B\) and for each \(n\) there exists \(x\geq n\) such that each of the \(2^{k-1}\) intervals \([x-n, x+n]\), \([2x-n, 2x+n],\dots,[2^{k-1}x-n, 2^{k-1}x+n]\) is contained in \(B\).
Zoltán Füredi +2 more
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Homogenization of Elliptic Difference Operators
SIAM Journal on Mathematical Analysis, 2001We develop some aspects of general homogenization theory for second order elliptic difference operators and consider several models of homogenization problems for random discrete elliptic operators with rapidly oscillating coefficients. More precisely, we study the asymptotic behavior of effective coefficients for a family of random difference schemes ...
Andrey Piatnitski, Elisabeth Remy
openaire +3 more sources
Deadlocks in Different Operating Systems
2015 12th International Conference on Information Technology - New Generations, 2015The world has evolved so quickly in the field of information and technology, especially in those parts that include computer engineering. Operating systems are a very big proof that demonstrates this evolution. We were very interested in the treatment of this theme starting from the curiosity on how deadlocks perform in different OS, especially in ...
Helidon Karcanaj +3 more
openaire +1 more source

