Results 161 to 170 of about 110,219 (262)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Separation of Time Scales in Weakly Interacting Diffusions. [PDF]

Arch Ration Mech Anal
Adams ZP, Engel M, Gvalani RS.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Long-Time Dynamics for the Kelvin-Helmholtz Equations Close to Circular Vortex Sheets. [PDF]

Arch Ration Mech Anal
Murgante F, Roulley E, Scrobogna S.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Evaluation of operator experience and nickel-titanium retreatment file systems in curved root canals. [PDF]

Eur Oral Res
Özden İ, Çil A, Cilli B, Gökyar M, Ayhan T, Öveçoğlu HS.   +5 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

A Framework for Integrating Large Language Models into Memetic Algorithms. [PDF]

Biomimetics (Basel)
Sakharov M.
europepmc   +1 more source

RETRACTION: Identification of Recurrence‐Related MicroRNAs in Hepatocellular Carcinoma Following Liver Transplantation

Molecular Oncology, EarlyView.
RETRACTION: Z.‐B. Han, L. Zhong, M.‐J. Teng, J.‐W. Fan, H.‐M. Tang, J.‐Y. Wu, H.‐Y. Chen, Z.‐W. Wang, G.‐Q. Qiu, and Z.‐H. Peng, “Identification of Recurrence‐Related MicroRNAs in Hepatocellular Carcinoma following Liver Transplantation,” Molecular Oncology 6, no. 4 (2012): 445‐457, https://doi.org/10.1016/j.molonc.2012.04.001.
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source