Results 61 to 70 of about 3,812,687 (259)

Approximation for Difference of Lupas and Some Classical Operators

open access: yes, 2020
The approximation of difference of two linear positive operators having different basis functions is discussed in the present article. The quantitative estimates in terms of weighted modulus of continuity for the difference of Lupas operators and the ...
Malik, Neha   +3 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

On the Correctness of Polynomial Difference Operators

open access: yesJournal of Siberian Federal University. Mathematics & Physics, 2015
Summary: The correctness Cauchy problem is explored for a polynomial difference operator. The easily verifiable sufficient condition correctness for the Cauchy problem for a polynomial difference operator with constant coefficients is proved whose characteristic polynomial is homogeneous.
openaire   +3 more sources

Generalized powers of the difference operator [PDF]

open access: yesTransactions of the American Mathematical Society, 1958
has a long history and an extensive literature, the most elegant and systematic accounts of it being those of Norlund [4] and Milne-Thomson [3]. The study of the operator has taken several directions, the main ones being the Bernoulli numbers and polynomials associated with it, the inversion of the operator, and the solution of certain difference ...
openaire   +2 more sources

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Fourteenth Illinois Custom Spray Operators' Training School: summaries of presentations [PDF]

open access: yes, 1962
Made available in DSpace on 2016-03-17T21:24:36Z (GMT). No. of bitstreams: 2 7912186_1962.pdf: 7042136 bytes, checksum: 247e2ecc35c0da86f5c377e4e4d7cc49 (MD5) license.txt: 4846 bytes, checksum: 927d59ba442de31571446841df3d90ca (MD5) Previous issue date:
Illinois Custom Spray Operators' School
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Twentieth Illinois Custom Spray Operators' Training School: summaries of presentations [PDF]

open access: yes, 1968
Made available in DSpace on 2016-03-17T21:24:40Z (GMT). No. of bitstreams: 2 7912186_1968.pdf: 12610806 bytes, checksum: 284d4070ba917ccc8295a5e587255134 (MD5) license.txt: 4846 bytes, checksum: 927d59ba442de31571446841df3d90ca (MD5) Previous issue ...
Illinois Custom Spray Operators' School
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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