Results 61 to 70 of about 110,219 (262)
Representing and Operating with Model Differences [PDF]
, 2008 Models and metamodels play a cornerstone role in Model-Driven Software Development (MDSD). Models conform to metamodels, which usually specify domain-specific languages that allow to represent the various facets of a system in terms of models. This paper discusses the problem of calculating differences between models conforming to arbitrary metamodels,
José Eduardo Rivera, Antonio Vallecillo
openaire +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
On the Definitions of Nabla Fractional Operators
Abstract and Applied Analysis, 2012 We show that two recent definitions of discrete nabla fractional sum operators are related. Obtaining such a relation between two operators allows one to prove basic properties of the one operator by using the known properties of the other. We illustrate
Thabet Abdeljawad, Ferhan M. Atici
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Optimal Difference Operator Selection [PDF]
, 2008 Differential operators are essential in many image processing applications. Previous work has shown how to compute derivatives more accurately by examining the image locally, and by applying a difference operator which is optimal for each pixel neighborhood.
Peter Veelaert, Kristof Teelen
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Numerical algorithms for the time-space tempered fractional Fokker-Planck equation
Advances in Difference Equations, 2017 This paper aims to provide the high order numerical schemes for the time-space tempered fractional Fokker-Planck equation in a finite domain. The high order difference operators, called the tempered and weighted and shifted Lubich difference operators ...
Xiaorui Sun, Fengqun Zhao, Shuiping Chen
doaj +1 more source