Results 171 to 180 of about 17,412,363 (205)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

International Differences in Entrepreneurship [PDF]

Christopher Woodruff, David McKenzie, Suresh de Mel   +2 more
core   +3 more sources

Sex Differences in Coronary Disease Health Status Outcomes: the ISCHEMIA Trial. [PDF]

Eur Heart J Qual Care Clin Outcomes
Grodzinsky A, Cho YJ, Jones PG, Shaw L, Merz CNB, Boden W, Stone G, Mark DB, Spertus JA, Maron DJ, Hochman JS, Reynolds HR.   +11 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Moderation with a latent class variable: A tutorial and example. [PDF]

Behav Res Methods
Arch DAN, Nylund-Gibson K, Ing M.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Amelioration of gentamicin-induced acute kidney injury by trifluoperazine: in vivo mechanistic insights. [PDF]

Sci Rep
Goda AE, Almosilhy NA, El-Mahdy NA.
europepmc   +1 more source

The role of socioeconomic position in use of systemic anticancer therapy. [PDF]

ESMO Real World Data Digit Oncol
Nielsen LH, Poulsen LØ, Falkmer U, Dalton SO, Olsen MH, Severinsen MT, Szejniuk WM, Haslund CA, Vistisen AK, Johnsen SP, Bøgsted M, Brøndum RF.   +11 more
europepmc   +1 more source

Single-cell analysis of inhibitory efferent neurons of the zebrafish lateral line. [PDF]

PLoS One
Manuel R, Ahemaiti A, Tuz-Sasik MU, Boije H.   +3 more
europepmc   +1 more source