Results 91 to 100 of about 4,888,790 (252)

Differentiable architecture search-based automatic modulation recognition for multi-carrier signals

open access: yesTongxin xuebao
Considering the lack of a general multi-carrier signal dataset in urban multipath channels, and the challenge of recognizing the modulation types of distorted signals at low signal-to-noise ratio (SNR), a differentiable architecture search-based (DARTS ...
LI Jie, LI Jing, LYU Lu, GONG Fengkui
doaj   +2 more sources

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

open access: yesAdvanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang   +12 more
wiley   +1 more source

DEff-ARTS: differentiable efficient ARchiTecture search

open access: yes, 2020
Manual design of efficient Deep Neural Networks (DNNs) for mobile and edge devices is an involved process which requires expert human knowledge to improve efficiency in different dimensions. In this paper, we present DEff-ARTS, a differentiable efficient
Merrett, Geoff   +3 more
core   +1 more source

Thioredoxin‐2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation

open access: yesAdvanced Science, EarlyView.
Endothelial TRX2 preserves bone homeostasis by retaining FOXO3a at mitochondria and limiting TRAIL production. Loss of TRX2 or oxidative stress releases FOXO3a for nuclear translocation, increasing endothelial TRAIL secretion and driving osteoclast formation and bone loss.
Chi Zhan   +10 more
wiley   +1 more source

Maternal Hyperglycemia Disrupts Cerebral Cortex Development Through the Foxp1‐Dll1‐Notch Axis

open access: yesAdvanced Science, EarlyView.
Maternal hyperglycemia disrupts offspring cortical development through a Foxp1–Dll1–Notch signaling axis. In a PGDM mouse model, intrauterine hyperglycemia decreases cortical thickness and perturbs neuronal layering by downregulating Foxp1, which transcriptionally regulates the Notch ligand Dll1.
Longkai He   +12 more
wiley   +1 more source

$\beta$-DARTS++: Bi-level Regularization for Proxy-robust Differentiable Architecture Search

open access: yes, 2023
Neural Architecture Search has attracted increasing attention in recent years. Among them, differential NAS approaches such as DARTS, have gained popularity for the search efficiency.
Bai, Lei   +5 more
core  

Multi‐Omics Analyses Identify Candidate Genes Associated With Stage‐Specific Quality Formation in Mulching‐Treated Moso Bamboo Shoots

open access: yesAdvanced Science, EarlyView.
Organic mulching reprograms Moso bamboo shoot development, enhancing yield and nutritional quality. This multi‐omics study reveals that coordinated metabolic, transcriptional, and post‐transcriptional regulation drives stage‐specific quality formation, offering comprehensive insights into how this agricultural practice improves crop performance and ...
Bo Wang   +7 more
wiley   +1 more source

Acinar‐Derived Organoids Reveal Stage‐Specific Control of Acinar Plasticity

open access: yesAdvanced Science, EarlyView.
An acinar‐derived organoid system maintains adult pancreatic acinar identity ex vivo, converts it along an ordered acinar‐to‐ductal‐like trajectory, and then partially restores it. Each transition carries its own signal requirement, with EGF/EGFR initiating conversion and a staged glucocorticoid–IGF1R switch driving redifferentiation.
Yongfei Hou   +10 more
wiley   +1 more source

Therapeutic Peptide‐Programmed Liquid‐Crystalline Topology Switching for pH‐Gated Postoperative Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan   +12 more
wiley   +1 more source

SR-DARTS: Robust Differentiable Neural Architecture Search with Stability Regularization

open access: yesContemporary Mathematics
Neural Architecture Search (NAS) has emerged as a powerful tool to find the best neural architectures with minimal manual intervention. However, existing NAS approaches suffer from poor robustness, because the search process is sensitive to the noise and hyperparameter settings.
Huakun Wu, Gusheng Tian, Peng Zhang
openaire   +1 more source

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