Results 41 to 50 of about 4,888,790 (252)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Architecture-aware minimization (A2M): how to find flat minima in neural architecture search

Machine Learning: Science and Technology
Neural architecture search (NAS) has become an essential tool for designing effective and efficient neural networks. In this paper, we investigate the geometric properties of neural architecture spaces commonly used in differentiable NAS methods ...
Matteo Gambella, Fabrizio Pittorino, Manuel Roveri   +2 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

emoDARTS: Joint Optimization of CNN and Sequential Neural Network Architectures for Superior Speech Emotion Recognition

IEEE Access
Speech Emotion Recognition (SER) is crucial for enabling computers to understand the emotions conveyed in human communication. With recent advancements in Deep Learning (DL), the performance of SER models has significantly improved. However, designing an
Thejan Rajapakshe, Rajib Rana, Sara Khalifa, Berrak Sisman, Bjorn W. Schuller, Carlos Busso   +5 more
doaj   +1 more source

Partially-Connected Differentiable Architecture Search for Deepfake and Spoofing Detection

, 2021
International audienceThis paper reports the first successful application of a differentiable architecture search (DARTS) approach to the deepfake and spoofing detection problems. An example of neural architecture search, DARTS operates upon a continuous,
Panariello, Michele, Wanying Ge, Jose Patino, Ge, Wanying, Evans, Nicholas, Michele Panariello, Nicholas Evans, Patino, Jose, Todisco, Massimiliano, Massimiliano Todisco   +9 more
core   +1 more source

2D Skeletal Muscle Thin Film Actuators Enhance Efficiency of Biohybrid Robots

Advanced Functional Materials, EarlyView.
2D skeletal muscle thin film actuators generate millinewton‐scale forces and millimeter‐scale strokes while remaining functional for over 30 days. Their force density is 20‐fold higher than 3D skeletal muscle actuators, enabling multi‐fin robots with tunable speed and multidirectional steering.
Maheera Bawa, Arielle Berman, Laura Schwendeman, Ferdows Afghah, Seanbiron Johnson, Ritu Raman   +5 more
wiley   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Phase Diagrams Enable Solid‐State Battery Design

Advanced Materials Interfaces, EarlyView.
Batteries are non‐equilibrium devices with inherent thermodynamic driving forces to react at interfaces, regardless of kinetics or operating conditions. Chemical potential mismatches across interfaces are dissipated via interfacial reactions. In this work, it is illustrated how phase diagrams and chemical potential maps predict degradation pathways but
Nathaniel L. Skeele, Matthias T. Agne
wiley   +1 more source

Noise-Disruption-Inspired Neural Architecture Search with Spatial–Spectral Attention for Hyperspectral Image Classification

Remote Sensing
In view of the complexity and diversity of hyperspectral images (HSIs), the classification task has been a major challenge in the field of remote sensing image processing.
Aili Wang, Kang Zhang, Haibin Wu, Shiyu Dai, Yuji Iwahori, Xiaoyu Yu   +5 more
doaj   +1 more source

$α$ DARTS Once More: Enhancing Differentiable Architecture Search by Masked Image Modeling

CoRR, 2022
Differentiable architecture search (DARTS) has been a mainstream direction in automatic machine learning. Since the discovery that original DARTS will inevitably converge to poor architectures, recent works alleviate this by either designing rule-based architecture selection techniques or incorporating complex regularization techniques, abandoning the ...
Bicheng Guo, Shuxuan Guo, Miaojing Shi, Peng Cheng 0001, Shibo He, Jiming Chen 0001, Kaicheng Yu   +6 more
openaire   +3 more sources