Results 201 to 210 of about 1,757,011 (294)

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Analysis and Synchronous Study of a Five-Dimensional Multistable Memristive Chaotic System with Bidirectional Offset Increments. [PDF]

Entropy (Basel)
Ding L, Xuan M.
europepmc   +1 more source

Transient Stiffness Patterning in Hydrogels Driven by Dissipative Mechanochemical Coupling

Advanced Functional Materials, EarlyView.
Force‐induced disulfide bond rupture in a polymer‐based hydrogel, coupled with chemical or electrochemical reoxidation, leads to the transient modulation of the hydrogel's stiffness properties. High spatiotemporal control is achieved by this dissipative process, enabling the development of out‐of‐equilibrium stiffness patterns and transient, dose ...
Roberto Baretta, Maria F. Pantano, Marco Frasconi   +2 more
wiley   +1 more source

A primer on variational inference for physics-informed deep generative modelling. [PDF]

Philos Trans A Math Phys Eng Sci
Glyn-Davies A, Vadeboncoeur A, Akyildiz OD, Kazlauskaite I, Girolami M.   +4 more
europepmc   +1 more source

Eco‐Fabricated Nanowave‐Textured Implants Drive Microtubule‐Assisted Nuclear Mechanotransduction and Chromatin Modification: Biophysical Priming for Osteogenesis and Bone Regeneration

Advanced Functional Materials, EarlyView.
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong, Ji‐Young Yoon, Junyong Ahn, Byunghak Lee, Sung‐Min Park, Jae‐Heon Kim, Buuvee Bayarkhangai, Yu Jin Kim, Sak Lee, Jonathan C. Knowles, Moon‐Young Kim, DongJun Lee, Sang‐Hoon Rhee, Hae‐Hyoung Lee, Hae‐Won Kim, Jung‐Hwan Lee   +15 more
wiley   +1 more source

Mathematical modeling of allelopathic stimulatory phytoplankton species using fractal-fractional derivatives. [PDF]

Sci Rep
Kumawat S, Bhatter S, Bhatia B, Purohit SD, Suthar DL.   +4 more
europepmc   +1 more source

Decoding the Structure of Benzodithiophene Polymers for High‐Efficiency Organic Solar Cells

Advanced Functional Materials, EarlyView.
This study reveals a unique solid mesophase in top‐performing benzodithiophene‐based polymers for solar cells, comprising stacked solid‐like and liquid‐like layers. Combining nanoscale fibrillar domains with amorphous regions, it introduces a new structural paradigm.
Matteo Sanviti, Sara Marina, Xabier Rodriguez‐Martínez, Jesika Asatryan, Valerio Di Lisio, Sandra Hultmark, Junkal Gutierrez, Eduardo Solano, Jeromy J. Rech, Eugenio L. Solla, Wei You, Agnieszka Tercjak, M. Eugenio Vázquez, Daniele Cangialosi, Christian Müller, Harald Ade, Jaime Martin   +16 more
wiley   +1 more source

2P-099 A Dynamic Model for Irreversible Differentiation in a Stem Cell System : Chaos Hypothesis(Development & Differentiation,The 47th Annual Meeting of the Biophysical Society of Japan)

, 2009
Chikara Furusawa, Kunihiko Kaneko
openalex   +2 more sources

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

Advanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo, Zaijin Tao, Zhenzhen Dai, Yinghua Gao, Chengzhen Chu, Cunyi Fan, Shen Liu, Xin Ma, Fangchun Jin, Zhengwei You, Jia Jiang   +10 more
wiley   +1 more source

Computational analysis of a mathematical model of hookworm infection. [PDF]

Sci Rep
Shafique U, Al-Shamiri MM, Raza A, Ahmed N, Rafiq M, Fadhal E, Ceesay B.   +6 more
europepmc   +1 more source