Results 171 to 180 of about 12,501,815 (346)

Variable Metric Forward–Backward Algorithm for Minimizing the Sum of a Differentiable Function and a Convex Function

Journal of Optimization Theory and Applications, 2013
É. Chouzenoux, J. Pesquet, A. Repetti
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Dependence results on almost periodic and almost automorphic solutions of evolution equations

Electronic Journal of Differential Equations, 2010
We consider the semilinear evolution equations $x'(t) = A(t) x(t) + f(x(t), u(t),t)$ and $x'(t) = A(t) x(t) + f(x(t), zeta,t)$ where $A(t)$ is a unbounded linear operator on a Banach space X and f is a nonlinear operator.
Joel Blot, Philippe Cieutat, Gaston M. N'Guerekata   +2 more
doaj  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Parameterized inequalities based on three times differentiable functions

Boundary Value Problems
This paper presents a general identity including two real parameters for three times differentiable functions. By using this equality, we prove several inequalities by using diverse function classes such as convex function, bounded function, Lipschitzian
Bouharket Benaissa, Noureddine Azzouz, Hüseyin Budak   +2 more
doaj   +1 more source

Systems of functional differential inequalities and functional differential systems [PDF]

Pacific Journal of Mathematics, 1976
openaire   +3 more sources

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga   +5 more
wiley   +1 more source

UNA APROXIMACIÓN DE NÚMEROS DIFUSOS DE TIPO TRAPEZOIDAL AN APPROXIMATION OF TRAPEZOIDAL TYPE FUZZY NUMBERS

Ingeniare: Revista Chilena de Ingeniería, 2009
En este trabajo se presenta una aproximación para un número difuso de tipo trapezoidal por una secuencia de números difusos ε-diferenciables, es decir, números difusos cuya función de pertenencia es diferenciable en el interior del nivel ε.
Y Chalco-Cano, J Pedraza Arpasi, H Román-Flores, G Álvarez-Jáuregui   +3 more
doaj