Results 181 to 190 of about 12,319,152 (351)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

UNA APROXIMACIÓN DE NÚMEROS DIFUSOS DE TIPO TRAPEZOIDAL AN APPROXIMATION OF TRAPEZOIDAL TYPE FUZZY NUMBERS

open access: yesIngeniare: Revista Chilena de Ingeniería, 2009
En este trabajo se presenta una aproximación para un número difuso de tipo trapezoidal por una secuencia de números difusos ε-diferenciables, es decir, números difusos cuya función de pertenencia es diferenciable en el interior del nivel ε.
Y Chalco-Cano   +3 more
doaj  

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Hindsight/RREB-1 functions in both the specification and differentiation of stem cells in the adult midgut ofDrosophila [PDF]

open access: gold, 2015
Brittany L. Baechler   +4 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Distinct hydrologic response patterns and trends worldwide revealed by physics-embedded learning. [PDF]

open access: yesNat Commun
Ji H   +11 more
europepmc   +1 more source

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