Results 41 to 50 of about 1,173,776 (257)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Differentiable Halo Mass Prediction and the Cosmology-Dependence of Halo Mass Functions
The Open Journal of AstrophysicsModern cosmological inference increasingly relies on differentiable models to enable efficient, gradient-based parameter estimation and uncertainty quantification.
Jim Buisman, Florian List, Oliver Hahn
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Differentiable mapping of affine Qm and projective Pn spaces (m
Известия Томского политехнического университета: Инжиниринг георесурсов, 2009 It is proved that affine space mapping into manifolds of degenerate and non degenerate null-pairs of projective space are determined in invariant way by affine and projective spaces mapping.
E. T. Ivlev +2 more
doaj +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Differentiable mapping of affine Qn and projective Pn spaces
Известия Томского политехнического университета: Инжиниринг георесурсов, 2009 The authors have studies the fields of invariant geometric images occurring when mapping affine space into projective space. Using these geometric images it is shown that the affine space mappings into manifolds of degenerate and non degenerate null ...
M. A. Al-Khassani, E. A. Moldovanova
doaj +2 more sources
Mixed Approximation for Nonexpansive Mappings in Banach Spaces
Abstract and Applied Analysis, 2010 The mixed viscosity approximation is proposed for finding fixed points of nonexpansive mappings, and the strong convergence of the scheme to a fixed point of the nonexpansive mapping is proved in a real Banach space with uniformly Gâteaux differentiable ...
Qing-Bang Zhang +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Open mapping theorems for directionally differentiable functions [PDF]
, 2004 Open mapping theorems are proved for directionally differentiable Lipschitz continuous functions. It is indicated that generalizations to nonsmooth functions that are not directionally differentiable are possible.
Seierstad, Atle
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