Results 121 to 130 of about 2,264,558 (236)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Ventricular Fibrillation Without Hemodynamic Deterioration: An Electrocardiographic Paradox Explained by Heterotopic Heart Transplantation. [PDF]

JACC Case Rep
Zernikow J, Hintz I, Spethmann S, Gröschel J, Dagres N, Schoenrath F, Hindricks G, Knosalla C, Koehler F, Haverkamp W.   +9 more
europepmc   +1 more source

The role of cognitive functioning within the homeless population

, 2014
Few studies have investigated cognitive functioning within the homeless population but it has been recognised as asignificant difficulty within this group.
Dowling, Noreen
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Sex differences in diffusion-weighted imaging outcomes in autosomal dominant Alzheimer's disease. [PDF]

Brain Commun
Giudicessi A, Koops E, Baena A, Alvarez S, Vidal M, Martinez L, Bonillas Félix NA, Gonzalez I, Medrano R, Tristão-Pereira C, Malotaux V, He B, Vila-Castelar C, Jacobs HIL, Aguillon D, Cronin-Golomb A, Quiroz YT.   +16 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Extensive Cardiac Involvement in ANCA-Associated Vasculitis Presenting With Severe Aortic Regurgitation and Atrioventricular Block. [PDF]

JACC Case Rep
David-Pardo DG, Reyes-T RE, Luna G, Gómez I, Rojas-Marulanda J, Meza-González YA, Castillo HH, López CO, Jaimes-Castellanos CP, Vasquez-Rodriguez JF.   +9 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Fixel-based analysis reveals whole-brain white matter microstructural alterations in axial spondyloarthritis. [PDF]

Sci Rep
Wang W, Yang Y, Xue Y, Wang Y, Luo Y, Liu Y, Lu F, Shen G, Xiao Y, Liu Z, Xiong F.   +10 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source